Licorice root (Glycyrrhiza glabra) has a long history of use in traditional medicine systems, particularly in Traditional Chinese Medicine (TCM) and Ayurveda, to support stomach health and alleviate digestive complaints. In TCM, licorice is considered a harmonizing herb, often included in formulas to "tonify" the stomach, soothe digestive discomfort, and reduce inflammation of the mucous membranes. Traditional uses include the management of gastritis, stomach ulcers, heartburn, and indigestion. The demulcent (soothing) properties of licorice are thought to protect the stomach lining and promote mucous production, which may help buffer stomach acid and relieve symptoms of irritation.

Scientific research offers some support for these traditional uses, though the clinical evidence is limited and not always conclusive. Deglycyrrhizinated licorice (DGL) has been studied for its potential to treat peptic ulcers and functional dyspepsia, with some small trials and laboratory studies suggesting it may encourage mucous secretion and facilitate ulcer healing. However, most of the evidence is preliminary, and large, high-quality clinical trials are lacking.

Overall, while licorice root's use for stomach support is deeply rooted in tradition, there is moderate scientific rationale and some supportive data, but more robust clinical evidence is needed for widespread medical endorsement.