Mimosa pudica, commonly known as the "sensitive plant," has a documented history of use in traditional medicine systems, particularly Ayurveda and folk medicine, for supporting various aspects of the digestive system, including the stomach. Historically, the plant has been used to address gastric disturbances, dysentery, diarrhea, and as a general stomach tonic. Preparations from the roots, leaves, and seeds have been utilized to soothe gastrointestinal discomfort and to manage ulcers and inflammation in the gut. However, much of this use is based on anecdotal evidence and traditional practices rather than modern clinical studies.

Scientific validation for Mimosa pudica's effects on the stomach is limited and primarily restricted to in vitro or animal studies. Some research has indicated potential anti-ulcer and anti-inflammatory effects in animal models, with extracts reducing gastric lesions and protecting the gastric mucosa. The proposed mechanisms include antioxidant activity and modulation of inflammatory pathways. Nonetheless, rigorous human clinical trials assessing its efficacy and safety for stomach-related conditions are lacking. As such, while traditional use is well established and there are some promising preliminary findings, current scientific evidence does not robustly support its use for the stomach system. Its use remains primarily justified by tradition.