Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Jiaogulan (Gynostemma pentaphyllum) has a long history of use in traditional Chinese medicine and folk medicine, particularly in southern China, as an adaptogen and general health tonic. Historically, it has been consumed as a tea to promote vitality, longevity, and resilience against both physical and mental stress. The traditional belief is that jiaogulan helps to balance the body's systems and support the body's ability to adapt to various stressors, similar to the concept of "adaptogens" in herbal medicine.

Scientific studies investigating jiaogulan's effect on stress are relatively limited and preliminary. Some animal research suggests that compounds in jiaogulan, such as gypenosides, may influence the hypothalamic-pituitary-adrenal (HPA) axis and modulate stress responses. There is also some evidence that it may have anti-fatigue and anxiolytic (anxiety-reducing) effects in rodent models. However, robust clinical trials in humans specifically evaluating jiaogulan for stress reduction are lacking. While its traditional use for stress and adaptation is well-established, current scientific evidence is insufficient to strongly validate these effects in humans. Thus, its use for stress is primarily justified by traditional practices, with some early but inconclusive scientific interest.

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