Evidence supporting the use of: Schisandrins
For the health condition: Stress

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Schisandrins are bioactive compounds found in Schisandra chinensis, a plant widely used in Traditional Chinese Medicine (TCM). Historically, Schisandra berries have been classified as an "adaptogen," a term for substances believed to help the body resist physical, chemical, or biological stressors. In TCM, Schisandra is thought to "calm the spirit," improve mental function, and enhance resilience to stress, and it has been included in various formulations intended to support stress resistance and vitality.

Scientific research on Schisandrins and stress is limited but emerging. Some preclinical studies (mainly in animals and cell models) indicate that Schisandra extracts and Schisandrins may modulate the hypothalamic-pituitary-adrenal (HPA) axis, reduce stress-induced biochemical changes, and improve markers of cognitive and physical performance under stress. However, robust human clinical trials confirming these effects are lacking. Therefore, while the traditional use is strong and there is some preliminary scientific rationale, the current evidence base remains modest, and most claims are not yet validated by rigorous clinical research. As such, the use of Schisandrins for stress is primarily justified by tradition, supported by limited (but promising) scientific investigations.

More about Schisandrins
More about Stress

Other ingredients used for Stress

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7,8-Dihydroxyflavone
7-Keto-DHEA
Acetyl L-carnitine
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Agarwood
Agastache
Agmatine
Agrimony
Akebia
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Algal protein
Alpha lactalbumin
alpha-pinene
AMP-activated protein kinase (AMPK)
anemarrhena asphodeloides
anise
Anserina
antler
Antrodia camphorata
apigenin
Aralia
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arjun tree
arjuna
ashitaba
ashwagandha
asparagus
astragalus
baccosides
Bacopa
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bacoside
baicalein
baicalin
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banana
banyan
Basidiomycota
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benegut perilla (proprietary)
bergamot
betony
Bifidobacteria
Bifidobacterium bifidum
Bifidobacterium lactis
Bifidobacterium longum
biota seed
bird\'s nest
black ginger
Black spruce
black tea
bonito peptide
borage
brahmi
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Bupleurum
bupleurum falcatum
C-phycocyanin
calamus
Calea zacatechichi
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Canscora
Capitate Valerian
cardamom
caterpillar mushroom
catnip
catuaba
Celastrus
Centella asiatica
Centella triterpenes
chaga mushroom
chamomile
cherimoya
Chinese fleeceflower
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chuchuhuasi
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oat
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Products containing Schisandrins

We currently have no products on Vitabase that contain this ingredient.