Evidence supporting the use of: DHA (Docosahexaenoic Acid)
For the health condition: Strokes

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Docosahexaenoic Acid (DHA) has some scientific evidence supporting its use in the context of stroke, primarily based on preclinical animal studies and limited human epidemiological data. DHA is an omega-3 fatty acid integral to brain health, and its neuroprotective effects have been investigated for potential benefits in stroke prevention and recovery. Experimental studies in rodents have shown that DHA administration, both before and after induced stroke, can reduce brain infarct size, decrease inflammation, and improve functional outcomes. Mechanistically, DHA may exert protective effects through anti-inflammatory, anti-apoptotic, and cell membrane-stabilizing actions.

However, clinical evidence in humans is limited. Some observational studies suggest that higher dietary intake or blood levels of DHA are associated with a lower risk of stroke, but these studies are not definitive and do not establish causality. Randomized controlled trials specifically assessing DHA supplementation for the prevention or treatment of acute stroke in humans are scarce, and results are inconclusive or show only modest benefits.

Overall, while animal studies and epidemiological data provide a rationale for further investigation, there is currently insufficient high-quality clinical evidence to recommend DHA as a standard treatment or adjunct therapy for stroke patients. The current evidence supports a rating of 2, reflecting promising preclinical data but a lack of robust human trials.

More about DHA (Docosahexaenoic Acid)
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