Evidence supporting the use of: Ginkgo flavones
For the health condition: Strokes

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Ginkgo flavones, primarily derived from Ginkgo biloba leaves, have been investigated for their potential neuroprotective effects, including their role in supporting or treating stroke. There is some scientific rationale behind their use: preclinical studies suggest that Ginkgo flavone glycosides possess antioxidant, anti-inflammatory, and anti-apoptotic properties, which could theoretically limit neuronal damage after ischemic events such as stroke. Additionally, Ginkgo extracts may improve microcirculation and inhibit platelet-activating factor, potentially reducing further vascular events.

However, the clinical evidence from randomized controlled trials is mixed and generally of low to moderate quality. A 2005 Cochrane review concluded that there was insufficient evidence to support the use of Ginkgo biloba for acute ischemic stroke recovery. Some more recent studies suggest possible improvements in cognitive recovery or neurological function in certain subgroups, but these results are not robust or widely replicated. Ginkgo is not a standard part of stroke treatment guidelines in Western medicine.

In summary, while there is some scientific interest and a plausible mechanism for Ginkgo flavones in stroke support, the clinical evidence remains weak and inconsistent. Use in this context is not supported by strong scientific validation, and more rigorous, large-scale studies would be needed to justify its routine use for stroke patients.

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