Evidence supporting the use of: Collagen Peptides
For the body system: Structural System

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Table of Contents

Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Collagen peptides are widely used to support the structural system, particularly for joint, bone, and skin health. Scientific studies have shown that oral supplementation with collagen peptides can improve skin elasticity and hydration, and may help reduce the appearance of wrinkles. For the musculoskeletal system, several randomized controlled trials have demonstrated that collagen peptide supplementation can support joint health by reducing pain and improving function in individuals with osteoarthritis or joint discomfort. Additionally, there is some evidence suggesting that collagen peptides may enhance bone mineral density, particularly in postmenopausal women, though further research is needed to confirm these effects and clarify optimal dosing.

The mechanism is believed to involve the breakdown of ingested collagen into bioactive peptides, which are then absorbed and can stimulate the synthesis of new collagen and extracellular matrix components in the body. This supports the integrity and repair of connective tissues, including cartilage, tendons, ligaments, and skin. While the evidence base is growing, most studies are of moderate duration and often utilize specific branded collagen preparations, so results may not be generalizable to all collagen supplements. Overall, the use of collagen peptides for supporting structural system health is supported by a moderate level of scientific evidence, especially for joint and skin health, with ongoing research likely to clarify their full potential.

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