Evidence supporting the use of: Urolithin A
For the body system: Structural System
Synopsis
Source of validity: Scientific
Rating (out of 5): 3
Urolithin A is a metabolite produced by gut bacteria from ellagitannins, compounds found in pomegranates and some other fruits. Recent scientific research has explored Urolithin A’s effects on the structural system, particularly skeletal muscle and bone health. Preclinical studies have shown that Urolithin A can promote mitophagy (the selective degradation of damaged mitochondria), leading to improved mitochondrial function in muscle cells. Human clinical trials, though limited, indicate that supplementation with Urolithin A can improve muscle endurance and strength in older adults, which is relevant to the structural system's integrity and function.
Additionally, some animal studies suggest that Urolithin A may have a positive impact on bone health by reducing inflammation and oxidative stress, factors that contribute to bone degeneration. However, direct evidence in humans regarding bone density or fracture prevention is currently lacking. There is no significant historical or traditional use of Urolithin A for structural system support, as it is a relatively newly identified compound in scientific research.
In summary, the use of Urolithin A for supporting the structural system is grounded in emerging scientific evidence, particularly in relation to muscle health and mitochondrial function. However, larger and longer-term human studies are needed to fully validate its efficacy for broader aspects of the structural system such as bone health. The current evidence justifies a moderate rating.
Other ingredients that support Structural System
AlfalfaAlgal protein
arnica
bayberry
bee products
beef
bone protein
bovine protein
burdock
calcium
cartilage
chickweed
chondroitin
Cissus quadrangularis
collagen
copper
creatine
devil's claw
egg
elastin
eucommia
Eucommia ulmoides
fat liver oil
fibroblast growth factor
fish protein
glucosamine
Glycine
Glycosaminoglycans
hyaluronic acid
hydroxyproline
L-leucine
L-proline
magnesium
Marine lipid
Methylsulfonylmethane (MSM)
Microcrystalline hydroxyapatite concentrate (MCHC)
Milk
Moringa
N-acetyl-glucosamine
omega-3 fatty acids
phosphorus
Plankton
protein
Salmon Oil
silicon
slippery elm bark
strontium
trace minerals
turmeric
Urolithin A
vitamin B
vitamin C
vitamin D
vitamin K
Yucca
Zinc
Other body systems supported by Urolithin A
BrainCirculatory System
Gastrointestinal Tract
Heart
Mitochondria
Muscles
Structural System
