Evidence supporting the use of: Vitamin D (mixed)
For the body system: Structural System

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Synopsis

Source of validity: Scientific
Rating (out of 5): 5

Vitamin D is strongly supported by scientific evidence for its role in the structural system, particularly in maintaining bone health. Vitamin D facilitates the intestinal absorption of calcium and phosphorus, minerals that are critical for the formation and maintenance of healthy bones and teeth. Deficiency in vitamin D can lead to bone disorders such as rickets in children and osteomalacia or osteoporosis in adults. Numerous randomized controlled trials and meta-analyses have demonstrated that adequate vitamin D intake, either from sunlight exposure or supplementation, can significantly reduce the risk of fractures and bone loss, especially in older adults.

The “mixed” form typically refers to a combination of vitamin D2 (ergocalciferol) and D3 (cholecalciferol), both of which are converted in the liver and kidneys to the active form, calcitriol. Vitamin D3 is generally more effective at raising and maintaining adequate levels of vitamin D in the blood. The role of vitamin D in bone mineralization is so well established that leading health organizations, including the Institute of Medicine and the Endocrine Society, recommend its use for supporting the structural system. Thus, vitamin D is one of the most scientifically validated nutrients for structural system support.

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