Evidence supporting the use of: Vitamin D (unspecified)
For the body system: Structural System

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Synopsis

Source of validity: Scientific
Rating (out of 5): 5

Vitamin D is scientifically validated as essential for the health and maintenance of the structural system, particularly bones and teeth. Vitamin D plays a crucial role in calcium and phosphorus homeostasis, which are necessary for proper bone mineralization. Deficiency in vitamin D leads to rickets in children and osteomalacia or osteoporosis in adults—conditions characterized by weak or malformed bones. Numerous randomized controlled trials and meta-analyses have shown that adequate vitamin D intake, often in combination with calcium, reduces the risk of bone fractures and improves bone mineral density in populations at risk, such as the elderly. Vitamin D receptors are present in bone tissue, and the active form of vitamin D (calcitriol) promotes the absorption of calcium from the gut and its deposition in bone. Major scientific and medical organizations, including the Institute of Medicine (now the National Academy of Medicine) and the Endocrine Society, recommend vitamin D supplementation for maintaining bone health, especially in individuals with limited sun exposure or dietary intake. Thus, the use of vitamin D to support the structural system is robustly supported by scientific evidence.

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