Evidence supporting the use of: Vitamin (unspecified)
For the body system: Structural System

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Synopsis

Source of validity: Scientific
Rating (out of 5): 5

Vitamins play a critical role in supporting the structural system of the body, which includes bones, cartilage, ligaments, and connective tissues. Of particular importance are Vitamin D and Vitamin C. Vitamin D is essential for calcium absorption and bone mineralization; deficiency in this vitamin is linked to rickets in children and osteomalacia or osteoporosis in adults. Numerous clinical trials and meta-analyses have demonstrated that adequate Vitamin D intake, often in combination with calcium, reduces the risk of fractures and improves bone density (Bischoff-Ferrari et al., 2014). Vitamin C is necessary for the synthesis of collagen, a primary structural protein in bone, cartilage, and connective tissue. The historical recognition of scurvy—a disease resulting from Vitamin C deficiency—highlights its importance in maintaining connective tissue integrity. Other vitamins, such as Vitamin K, contribute to bone health through their role in the carboxylation of osteocalcin, a protein involved in bone mineralization. Overall, the use of vitamins to support the structural system is strongly supported by both historical evidence and robust scientific research, especially concerning bone and connective tissue health.

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