Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Gelatin is sometimes recommended to support healing after surgery based on its high content of amino acids such as glycine and proline, which are important for collagen synthesis. Collagen is a critical structural protein in the body, especially for skin, connective tissue, and wound healing. Several animal studies and limited human data suggest that gelatin or collagen supplementation may support wound repair, improve skin elasticity, and enhance tissue regeneration. For example, some research demonstrates improved wound healing in animals receiving gelatin hydrolysate, while isolated clinical trials in humans have shown modest improvements in skin hydration and elasticity. However, robust, well-controlled clinical trials specifically evaluating gelatin supplementation in post-surgical healing in humans are lacking.

Most clinical recommendations for gelatin after surgery are extrapolated from basic science or general studies on collagen peptides, rather than direct evidence for gelatin itself. While gelatin is generally recognized as safe and provides building blocks for tissue repair, it should not be considered a substitute for established wound care practices or medical nutrition therapy. Overall, the scientific support for gelatin in post-surgical healing is promising but limited, and more research—especially randomized controlled trials in surgical patients—is needed for definitive recommendations.

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