Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Belladonna (Atropa belladonna), also known as deadly nightshade, has a long history of traditional use in herbal medicine, particularly in Europe. Historically, it was used to treat a variety of ailments, including pain, muscle spasms, and inflammatory conditions. The active compounds in Belladonna, such as atropine, scopolamine, and hyoscyamine, are known as anticholinergics. These substances inhibit the parasympathetic nervous system by blocking acetylcholine receptors, thereby allowing the sympathetic nervous system to become more dominant. This pharmacological effect underpins the traditional rationale for its use in supporting or stimulating sympathetic nervous system activity, such as increasing heart rate, dilating pupils, and reducing secretions.

However, while the mechanism of action is scientifically understood, the use of Belladonna for “supporting” the sympathetic nervous system is primarily based on its traditional applications and not on contemporary scientific validation for wellness or enhancement purposes. Modern medicine uses purified compounds (e.g., atropine) for specific acute medical indications (like treating bradycardia or as antidotes), but not as general support for the sympathetic nervous system. Belladonna is not recommended for casual or routine use due to its toxicity and significant risk of severe side effects. Most current guidelines and scientific literature do not support its use as a general supplement for the sympathetic nervous system.

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