Synopsis

Source of validity: Scientific
Rating (out of 5): 4

Coffee, primarily due to its caffeine content, has scientific validation for its effects on the sympathetic nervous system. Caffeine is a well-known central nervous system stimulant that works by antagonizing adenosine receptors, leading to increased neuronal activity and the release of neurotransmitters such as norepinephrine and dopamine. This process stimulates the sympathetic nervous system, resulting in physiological responses such as increased heart rate, elevated blood pressure, and enhanced alertness. Numerous studies have documented these effects. A review in the journal Frontiers in Neuroscience (2017) highlights that caffeine reliably increases sympathetic nerve activity, leading to measurable cardiovascular and metabolic changes. Another study in Hypertension (2002) found that habitual coffee consumption is associated with heightened sympathetic nerve activity in humans. While most research focuses on caffeine rather than "mixed" coffee specifically, coffee as a beverage is one of the primary dietary sources of caffeine in the general population. There is less evidence for long-term modulation of the sympathetic nervous system, but the acute stimulatory effects are well established. Thus, the use of coffee to support or stimulate the sympathetic nervous system is rooted in clear scientific evidence, primarily due to its caffeine content and its physiological effects on the body.

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