Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Panax Ginseng has been traditionally used in Asian medicine for its adaptogenic properties, meaning it is believed to help the body resist stressors of various kinds. Scientific studies have explored its effects on the nervous system, particularly the sympathetic nervous system, which is involved in the "fight or flight" response. Research indicates that Ginseng's active compounds, called ginsenosides, may influence neurotransmitter release and modulate the hypothalamic-pituitary-adrenal (HPA) axis. Several animal and human studies have demonstrated that Ginseng can enhance physical and mental performance under stress, possibly by reducing fatigue, enhancing alertness, and supporting cognitive function. There is also evidence that Ginseng can modulate catecholamine levels (e.g., norepinephrine and epinephrine), hormones that play a central role in sympathetic nervous system activity. However, much of the human research is limited by small sample sizes and variable quality. Systematic reviews and meta-analyses conclude that Ginseng may have a modest but significant effect in supporting stress resilience and sympathetic nervous system function, but more rigorous clinical trials are needed for definitive conclusions. Overall, the evidence base is moderate, and the use of Panax Ginseng for sympathetic nervous system support is justified by both traditional practices and growing scientific research.

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