Evidence supporting the use of: Guayusa
For the body system: Sympathetic Nervous System
Synopsis
Source of validity: Traditional
Rating (out of 5): 3
Guayusa (Ilex guayusa) is a caffeinated leaf native to the Amazon rainforest and has been traditionally consumed by indigenous peoples in Ecuador and surrounding regions. Its primary use is as a stimulant beverage, much like yerba mate, to promote alertness, wakefulness, and energy. The traditional rationale for guayusa supporting the sympathetic nervous system stems from its naturally high caffeine content. Caffeine is well-known to stimulate the central nervous system, which, in turn, can activate the sympathetic (fight-or-flight) branch of the autonomic nervous system by increasing heart rate, blood pressure, and alertness.
While there is little direct scientific research specifically on guayusa’s effects on the sympathetic nervous system, its caffeine content is well established, and the physiological effects of caffeine have been extensively documented. Traditional Amazonian use supports its reputation as a natural stimulant, often consumed in the early morning or during nighttime vigils to ward off fatigue and enhance mental clarity. There is, however, a lack of clinical trials directly measuring guayusa’s impact on sympathetic nervous system markers. Thus, its use for this purpose is justified primarily by traditional practices and the known effects of caffeine, rather than direct scientific validation specific to guayusa.
Other ingredients that support Sympathetic Nervous System
acetyl l-carnitineashwagandha
basil
bergamot
beta caryophyllene
bасора
caffeine
capsaicinoids
citrus oil
citrus sinensis (proprietary)
cowage seed
eleuthero
ginkgo biloba
guarana
guayusa
jujube
kudzu
l-taurine
l-theanine
l-tyrosine
lavender
licorice root
lion's mane
magnesium
magnolia
muira puama
Acetyl-L-Tyrosine
omega-3 fatty acids
passionflower
phytocannabinoids
relora® (proprietary)
rhodiola
skullcap
vitamin B
whole adrenal glandular
jiaogulan
gastrodia
cardamom
lingusticum wallichii
yarrow
lemongrass
kanna
lotus seed
electrolytes blend (proprietary)
herbal blend (proprietary)
yohimbe
cayenne pepper
1,3,7-Trimethylpurine-2,6-dione
7,8-Dihydroxyflavone
Adrafinil
Adrenergic amines
Adrenaline
Brahmi
Bacopa
bacoside
Cortisol
Catecholamine
Convolvulus Pluricaulis
cola nut
Ephedra
Ephedrine
salt
yohimbine
Other body systems supported by guayusa
Adrenal CortexAdrenal Glands
Brain
Digestive System
Gastrointestinal Tract
Glandular System
Nerves
Parasympathetic Nervous System
Sympathetic Nervous System