Evidence supporting the use of: Fluoride
For the body system: Teeth

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Synopsis

Source of validity: Scientific
Rating (out of 5): 5

Fluoride is widely recognized and scientifically validated for its role in supporting dental health. Numerous studies have demonstrated that fluoride helps to prevent tooth decay by promoting the remineralization of tooth enamel and inhibiting the activity of cariogenic (cavity-causing) bacteria. The use of fluoride in community water fluoridation, toothpaste, and other dental products has been endorsed by major health organizations such as the World Health Organization (WHO), the Centers for Disease Control and Prevention (CDC), and the American Dental Association (ADA).

Research dating back to the mid-20th century indicates that populations with fluoridated water supplies experience significantly lower rates of dental caries compared to those without. The mechanism of action involves fluoride ions integrating into the hydroxyapatite crystals of tooth enamel, forming a more decay-resistant mineral called fluorapatite. Additionally, topical fluoride from toothpaste and mouth rinses acts directly on the tooth surface to repair early decay and inhibit bacterial metabolism.

Extensive systematic reviews and meta-analyses have confirmed the efficacy and safety of fluoride in reducing dental cavities when used at recommended levels. While excessive fluoride intake can lead to dental fluorosis, regulatory guidelines ensure safe concentrations in public health interventions. Thus, the use of fluoride to support dental health is strongly backed by scientific evidence.

More about fluoride
More about Teeth

Other body systems supported by fluoride

Gums
Teeth

Products containing fluoride

We currently have no products on Vitabase that contain this ingredient.