Evidence supporting the use of: Nimbidin
For the body system: Teeth

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Table of Contents

Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Nimbidin is a bioactive compound extracted from the seeds of the neem tree (Azadirachta indica). Traditionally, neem and its derivatives have been used in Ayurvedic and other traditional medicine systems for maintaining oral health, particularly for their antimicrobial and anti-inflammatory properties. In Indian culture, chewing neem sticks for cleaning teeth is a long-standing practice believed to prevent dental caries and gum disease. The use of nimbidin for supporting the teeth and oral cavity is therefore rooted primarily in traditional use. While some laboratory studies have shown that nimbidin exhibits antibacterial activity against oral pathogens and may reduce inflammation, these findings are largely preclinical, and robust human clinical trials directly assessing its efficacy in dental health are lacking. As such, scientific validation remains limited. Most of the support for nimbidin's use in oral care comes from the broader use of neem extracts and anecdotal evidence rather than well-controlled clinical research specifically on nimbidin. In summary, nimbidin is used to support the teeth body system primarily due to traditional practices, with only preliminary scientific evidence suggesting potential oral health benefits.

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