Pellitory (most commonly Parietaria officinalis or Anacyclus pyrethrum, also known as Pellitory-of-Spain or Akarkara) has a long history of traditional use for oral and dental health, particularly in Ayurvedic, Unani, and European herbal medicine. Traditionally, Pellitory root preparations were employed for toothache, as a remedy to relieve dental pain and stimulate saliva. The root was often chewed or used in poultices applied directly to the gums and teeth. The tingling, numbing sensation produced by its constituents (notably alkylamides such as pellitorine) was thought to help with oral discomfort.

While these traditional applications are well-documented in herbal texts and ethnobotanical records, modern scientific research on Pellitory’s efficacy for dental health is limited. There is some pharmacological evidence that alkylamides from Pellitory can have local anesthetic and sialogogue (saliva-stimulating) effects, which may temporarily relieve toothache or dry mouth. However, robust clinical trials validating its effectiveness or safety for ongoing dental use are lacking. Thus, its reputation for supporting the "teeth" body system is grounded primarily in tradition, with only preliminary pharmacological support and no strong scientific consensus.