Evidence supporting the use of: Pyrophosphate
For the body system: Teeth

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Synopsis

Source of validity: Scientific
Rating (out of 5): 4

Pyrophosphate is scientifically validated for its use in supporting dental health, specifically in the prevention of dental calculus (tartar) formation. Pyrophosphates, such as tetrasodium pyrophosphate and disodium pyrophosphate, are commonly included in toothpastes and oral care products. Their primary mechanism involves binding to calcium and magnesium ions in saliva, thereby inhibiting these ions from precipitating onto teeth and forming calculus. This action helps maintain cleaner tooth surfaces and can reduce the risk of gum disease associated with tartar buildup.

Numerous studies and systematic reviews have confirmed the efficacy of pyrophosphates in reducing supragingival calculus accumulation compared to non-pyrophosphate toothpastes. For example, a review published in the Journal of Clinical Dentistry (2014) confirmed that pyrophosphate-containing toothpastes consistently reduce calculus formation without significant adverse effects. Regulatory bodies such as the American Dental Association (ADA) recognize and approve the use of pyrophosphates in dentifrice formulations for these purposes.

However, it is important to note that while pyrophosphate is effective at preventing tartar, it does not reverse existing calculus and is not a replacement for mechanical removal by dental professionals. Overall, the inclusion of pyrophosphate in oral health products is well-supported by scientific evidence, justifying its widespread use for maintaining dental cleanliness and supporting overall oral health.

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Other body systems supported by pyrophosphate

Teeth

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