Evidence supporting the use of: Stannous Chloride
For the body system: Teeth
Synopsis
Source of validity: Scientific
Rating (out of 5): 5
Stannous chloride (SnCl2) is a compound commonly used in dental products, particularly toothpaste, due to its demonstrated efficacy in supporting oral health. The scientific validation for its use comes from numerous clinical studies showing that stannous ions (delivered as stannous fluoride or stannous chloride) provide multiple oral health benefits. These include reducing dental caries (cavities), alleviating dentinal hypersensitivity, and significantly decreasing gingivitis and plaque formation. Stannous chloride works by depositing a protective layer over exposed dentin, thus reducing sensitivity, and by exerting antibacterial effects that disrupt the metabolic activity of oral biofilm, thereby inhibiting the growth of harmful bacteria. Moreover, the stannous ion has been shown to reduce enamel erosion and provide stain control. Major dental associations, including the American Dental Association (ADA), recognize the benefits of stannous-containing toothpaste formulations. While stannous fluoride is more commonly used in consumer products than stannous chloride, both deliver the beneficial stannous ion. The evidence base supporting these effects is robust, consisting of systematic reviews, randomized controlled trials, and decades of clinical use. Therefore, the use of stannous chloride in supporting the teeth is strongly supported by scientific evidence.
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