Evidence supporting the use of: Fadogia agrestis
For the body system: Testosterone

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Table of Contents

Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Fadogia agrestis is a shrub native to Africa, traditionally used in Nigerian folk medicine as an aphrodisiac and for male reproductive health. Most of the support for its use to enhance testosterone or support the male reproductive system comes from traditional practices and anecdotal reports, rather than robust scientific validation. Existing scientific studies are very limited, and almost all are animal studies—primarily in rats. These studies suggest that extracts of Fadogia agrestis may increase serum testosterone levels and support sexual behavior in rodents. However, the mechanisms remain unclear, and the relevance of these findings to humans is uncertain due to differences in physiology and a lack of controlled human trials. No high-quality, peer-reviewed clinical trials in humans have been published as of June 2024. Thus, while the traditional use is well documented, current scientific evidence is insufficient to strongly support claims that Fadogia agrestis boosts testosterone in humans. Concerns also exist regarding the safety and potential toxicity at higher doses based on animal data. In summary, Fadogia agrestis is primarily used for testosterone support based on traditional use with only weak preliminary scientific evidence.

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