Evidence supporting the use of: Fadogia agrestis
For the health condition: Testosterone (low)

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Synopsis

Source of validity: Traditional
Rating (out of 5): 1

Fadogia agrestis is primarily used in traditional African medicine as an aphrodisiac and to support male sexual health, including claims related to testosterone enhancement. The plant has a history of use among indigenous communities in Nigeria and other parts of West Africa, where it is consumed in various forms for purported benefits on libido and fertility. However, robust scientific evidence supporting these claims is lacking. Most available research consists of a handful of animal studies—mainly in rodents—suggesting possible increases in serum testosterone levels following Fadogia agrestis extract administration. These studies often use high doses and short durations, and their results have not been replicated in human trials. No significant, peer-reviewed clinical studies in humans exist as of 2024. Furthermore, some animal studies have raised concerns about potential toxicity at higher doses. Thus, while traditional use supports its reputation for addressing low testosterone and related symptoms, scientific validation is minimal, and the overall quality of evidence is low. Fadogia agrestis should be approached with caution, and individuals considering its use should consult healthcare professionals, as its efficacy and safety in humans remain unestablished.

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