Evidence supporting the use of: Uridine monophosphate
For the health condition: Thinking (cloudy)
Synopsis
Source of validity: Scientific
Rating (out of 5): 2
Uridine monophosphate (UMP) has been investigated in scientific studies for its potential cognitive benefits, particularly relating to memory and brain function. Preclinical research, primarily in animal models, has shown that UMP, especially when combined with other compounds like choline and DHA (docosahexaenoic acid), may support synaptic formation and neuroplasticity, processes important for cognitive function. Some studies suggest that uridine supplementation can enhance phospholipid synthesis in the brain, which is thought to support neuronal membrane health and potentially ameliorate symptoms of "brain fog" or cognitive cloudiness. However, direct evidence in humans is limited. Small clinical trials in populations with cognitive impairment (such as mild Alzheimer's disease) have investigated combinations containing uridine, but it is difficult to isolate uridine's specific effect due to the multi-ingredient nature of these supplements. There is a lack of large, well-controlled studies evaluating UMP as a monotherapy for "cloudy thinking" in healthy adults. In summary, while there is a plausible biological rationale and encouraging preclinical data, the evidence base in humans is currently preliminary and not robust. UMP is not a traditional remedy for cognitive complaints, and its use is grounded more in emerging neuroscience than in clinical practice or historical precedent. Therefore, the evidence supporting its use for "cloudy thinking" rates as modest (2/5), pending further research.
More about Uridine monophosphate
More about Thinking (cloudy)
Other health conditions supported by Uridine monophosphate
Alzheimer's DiseaseCancer Treatment (reducing side effects)
Chemotherapy (reducing side effects)
Concentration (poor)
Dementia
Depression
Memory and Brain Function
Peripheral Neuropathy
Thinking (cloudy)