Synopsis

Source of validity: Scientific
Rating (out of 5): 2

L-Arginine is a semi-essential amino acid that serves as a precursor to nitric oxide (NO), a molecule involved in vasodilation and regulation of vascular tone. The rationale for its use in thrombosis centers on the role of NO in inhibiting platelet aggregation and promoting blood vessel relaxation, theoretically reducing the risk of clot formation. Several animal studies and in vitro experiments suggest that L-arginine supplementation can enhance NO production and thereby exert antithrombotic effects. However, clinical evidence in humans remains limited and inconsistent. Some small clinical trials have investigated L-arginine in patients with cardiovascular disease, noting improvements in endothelial function, but results on its direct impact on thrombosis are inconclusive. Major clinical guidelines do not recommend L-arginine as a treatment or preventive measure for thrombosis due to insufficient high-quality evidence. Overall, while the mechanistic basis is plausible and there is some preliminary scientific support, robust human data demonstrating efficacy and safety are lacking. Therefore, the evidence supporting the use of arginine specifically for thrombosis is weak (rated 2/5), and its clinical use for this indication is not widely accepted.

More about Arginine
More about Thrombosis

Other ingredients used for Thrombosis

Other health conditions supported by Arginine

Products containing Arginine