Evidence supporting the use of: Glyceryl monolaurate
For the health condition: Thrush

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Glyceryl monolaurate (GML) is a naturally occurring monoglyceride found in coconut oil and breast milk, known for its antimicrobial properties. Scientific research has demonstrated that GML exhibits broad-spectrum antimicrobial activity, including efficacy against Candida albicans, the primary fungal organism responsible for thrush (oral candidiasis). In vitro studies show that GML can disrupt the biofilm and cell membrane integrity of Candida species, thereby inhibiting their growth and pathogenicity. However, most of the available evidence comes from laboratory studies rather than clinical trials in humans. There is limited but promising data suggesting that GML could be effective as an adjunct treatment for thrush, especially in topical formulations. Some patents and experimental products have explored its use, but as of now, there are no large-scale, high-quality clinical trials confirming its efficacy and safety for treating thrush in humans. Thus, while the mechanistic and in vitro evidence is encouraging and provides a scientific rationale for its use, robust clinical validation is lacking, resulting in a moderate evidence rating.

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