Evidence supporting the use of: Lactobacillus rhamnosus
For the health condition: Thrush

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Lactobacillus rhamnosus is a probiotic bacterium that has been studied for its potential to support or treat thrush (oral or vaginal candidiasis), a condition caused by overgrowth of Candida species. There is some scientific evidence supporting its use, though the quality and consistency of the data are moderate.

Several clinical studies and in vitro experiments suggest that L. rhamnosus, particularly the GG strain, can inhibit the growth and adhesion of Candida albicans to mucosal surfaces. The proposed mechanisms include competitive exclusion, the production of lactic acid (which lowers pH), and enhancement of the host’s immune response. Some trials, particularly in women with recurrent vulvovaginal candidiasis, have shown that oral or vaginal administration of L. rhamnosus can reduce the risk of recurrence or support conventional antifungal therapy.

However, results are mixed, and many studies are small or lack rigorous controls. While there is scientific validation for its use, more large-scale, well-designed clinical trials are needed to confirm efficacy and optimal dosing regimens. In summary, L. rhamnosus is used to support or treat thrush based on a modest but growing body of scientific evidence, though it should not be considered a standalone therapy for severe or persistent infections.

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