Evidence supporting the use of: Bugleweed (unspecified)
For the body system: Thyroid Gland

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Bugleweed, particularly the species Lycopus europaeus and Lycopus virginicus, has a long history of traditional use in European and North American herbal medicine for supporting the thyroid gland, especially in cases of mild hyperthyroidism (overactive thyroid). Historical records and herbal texts describe bugleweed’s use in managing symptoms such as palpitations, anxiety, and mild goiter, likely due to its purported ability to inhibit the binding of thyroid-stimulating antibodies and decrease thyroid hormone synthesis. The herb contains compounds such as lithospermic acid, which are thought to interfere with thyroid-stimulating hormone (TSH) activity and peripheral conversion of thyroxine (T4) to triiodothyronine (T3).

Despite these traditional uses, scientific evidence is limited. Some animal and in vitro studies support the idea that bugleweed extracts may reduce thyroid hormone levels, but well-designed human clinical trials are lacking. There is no robust scientific consensus or regulatory approval for bugleweed in thyroid management. Therefore, its use remains primarily based on traditional knowledge rather than strong empirical evidence. Caution is advised, especially in individuals with thyroid disorders or those taking thyroid medication, due to the potential for herb-drug interactions and adverse effects.

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