Evidence supporting the use of: Selenium ascorbate
For the body system: Thyroid Gland

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Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Selenium ascorbate is a compound that combines selenium, an essential trace mineral, with ascorbic acid (vitamin C). Selenium is well-documented for its critical role in thyroid health, primarily because it is required for the synthesis and activity of selenoproteins, including the family of enzymes known as iodothyronine deiodinases. These enzymes are responsible for the activation and deactivation of thyroid hormones (conversion of thyroxine/T4 to the more active triiodothyronine/T3). Selenium deficiency has been linked to various thyroid dysfunctions, including Hashimoto’s thyroiditis and Graves’ disease, and supplementation has been found to reduce thyroid peroxidase antibodies in some cases.

There is also evidence that vitamin C (ascorbic acid) may offer antioxidant protection for thyroid tissue, though this is less well established than selenium’s role. Selenium ascorbate, specifically, is not as well-studied as selenomethionine or sodium selenite in thyroid research, but it is presumed to provide bioavailable selenium and the antioxidant effects of vitamin C. Clinical trials and meta-analyses support the use of selenium supplementation in thyroid autoimmunity and mild dysfunction, but the evidence is moderate rather than robust. Thus, while selenium is scientifically validated for thyroid support, the specific combination as selenium ascorbate has less direct evidence, leading to a moderate evidence rating.

More about Selenium ascorbate
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Other body systems supported by Selenium ascorbate

Heart
Immune System
Male Reproductive System
Thyroid Gland

Products containing Selenium ascorbate

We currently have no products on Vitabase that contain this ingredient.