Evidence supporting the use of: Seleno Methionine
For the body system: Thyroid Gland

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Synopsis

Source of validity: Scientific
Rating (out of 5): 4

Seleno Methionine is a well-validated form of the essential trace element selenium, which plays a crucial role in thyroid gland function. Selenium is required for the biosynthesis and activity of selenoproteins, including the enzyme iodothyronine deiodinase, which is responsible for the conversion of thyroxine (T4) to the more active triiodothyronine (T3) in the thyroid gland. Several scientific studies and clinical trials have demonstrated that selenium supplementation can support thyroid health, particularly in populations with marginal or low selenium status. Specifically, selenium supplementation (often as seleno methionine, due to its high bioavailability) has been shown to reduce thyroid peroxidase antibody levels in individuals with autoimmune thyroiditis (such as Hashimoto's disease) and may help modulate immune responses and reduce inflammation in the thyroid tissue. A 2017 meta-analysis in the journal Thyroid concluded that selenium supplementation can be beneficial in reducing thyroid antibody titers and may improve mood and general well-being in patients with autoimmune thyroiditis. However, while evidence is strong for selenium's role in thyroid health, high doses can be toxic, so supplementation should be approached with care. There is consensus in the scientific literature that seleno methionine is an effective form for raising selenium status and supporting normal thyroid function, but it should not replace standard thyroid medications where indicated.

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