Relationship: Tinnitus and coenzyme Q10 (CoQ10)

Evidence supporting the use of: Coenzyme Q10 (CoQ10)
For the health condition: Tinnitus

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Synopsis

Source of validity: Scientific
Rating (out of 5): 1

Coenzyme Q10 (CoQ10) is sometimes used as a supplement by individuals with tinnitus, primarily based on limited scientific research rather than longstanding traditional use. The rationale for using CoQ10 in tinnitus is tied to its role as an antioxidant and its involvement in cellular energy production, particularly in the mitochondria. It has been hypothesized that oxidative stress and mitochondrial dysfunction may play a role in the pathogenesis of some cases of tinnitus, especially those associated with sensorineural hearing loss.

However, the scientific evidence supporting the use of CoQ10 for tinnitus is weak. The most notable study is a small, randomized, double-blind, placebo-controlled trial published in 2007 (Arq Neuropsiquiatr. 2007) involving 41 patients with chronic tinnitus. The study found a statistically significant improvement in tinnitus symptoms only in a subgroup of patients with low baseline CoQ10 levels, suggesting that supplementation may be beneficial only for individuals who are deficient. Other clinical trials are lacking, and systematic reviews (such as those by the Cochrane Library) conclude that there is insufficient evidence to recommend CoQ10 supplementation for tinnitus in the general population.

In summary, while there is a scientific rationale and some limited clinical data, the overall quality and quantity of evidence is low. CoQ10 is not widely endorsed by clinical guidelines for tinnitus, and more robust research is needed to establish its efficacy.

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Other ingredients used for Tinnitus

acetyl l-carnitine
coenzyme Q10 (CoQ10)
ginkgo biloba
magnesium
melatonin

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Evidence supporting the use of: Coenzyme Q10 (CoQ10)
For the health condition: Tinnitus

Table of Contents

Synopsis

Other ingredients used for Tinnitus

Other health conditions supported by coenzyme Q10 (CoQ10)

Products containing coenzyme Q10 (CoQ10)

Health Concerns

Brands

Evidence supporting the use of: Coenzyme Q10 (CoQ10)For the health condition: Tinnitus

Table of Contents

Synopsis

Other ingredients used for Tinnitus

Other health conditions supported by coenzyme Q10 (CoQ10)

Products containing coenzyme Q10 (CoQ10)

Evidence supporting the use of: Coenzyme Q10 (CoQ10)
For the health condition: Tinnitus