Evidence supporting the use of: Ginkgo Falvone Glycoside
For the health condition: Tinnitus

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Ginkgo Flavone Glycoside, a constituent derived from the Ginkgo biloba plant, has been traditionally used—especially in Europe and Asia—to manage a variety of circulatory and neurological conditions, including tinnitus. The rationale behind its use for tinnitus is based on Ginkgo biloba’s purported ability to improve blood flow, protect nerve cells, and reduce oxidative stress, which are thought to potentially benefit individuals suffering from this condition. Historical use in herbal medicine systems and anecdotal reports have contributed to its popularity for tinnitus management.

However, scientific validation for its efficacy is limited. Several randomized controlled trials (RCTs) and systematic reviews have been conducted, most notably the 2013 Cochrane review, which concluded that there is no convincing evidence that Ginkgo biloba is effective in treating tinnitus. Some earlier or smaller studies suggested mild benefit, but larger, well-controlled trials generally have not supported these findings. The evidence is further complicated by variability in Ginkgo extract preparations and study designs. As such, while Ginkgo Flavone Glycoside continues to be used largely based on traditional and popular use, robust clinical evidence supporting its effectiveness for tinnitus remains weak.

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