Evidence supporting the use of: Ginkgo Flavonglycosides
For the health condition: Tinnitus

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Ginkgo flavonglycosides, the active compounds in Ginkgo biloba extract, are used to support or treat tinnitus primarily based on scientific rationale, though the strength of the evidence is limited. Ginkgo biloba has long been used in traditional medicine for various circulatory disorders, and its standardized extracts (often containing 24% flavonglycosides) have been studied in clinical settings for tinnitus. The proposed mechanisms include improving microcirculation in the inner ear, antioxidant effects, and neuroprotective actions. However, systematic reviews and meta-analyses, such as those published in the Cochrane Database of Systematic Reviews (2013, 2022), have concluded that the overall benefit of Ginkgo biloba for tinnitus is minimal to none compared to placebo. Some individual studies have reported modest improvements, but these are often small, methodologically limited, or conflicting. Major clinical guidelines generally do not recommend Ginkgo biloba for tinnitus due to insufficient evidence of efficacy. In summary, while Ginkgo flavonglycosides are used for tinnitus based on plausible mechanisms and some positive studies, the overall scientific validation is weak, and consistent, high-quality evidence supporting its effectiveness is lacking.

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