Evidence supporting the use of: Ginkgoside
For the health condition: Tinnitus

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Ginkgoside, the active compound found in Ginkgo biloba extracts, has been traditionally used in herbal medicine, particularly in Europe and Asia, to support cognitive function and alleviate symptoms like tinnitus (ringing in the ears). The rationale stems from Ginkgo's purported ability to improve blood flow, especially to the brain and inner ear, which is thought to help with auditory disorders such as tinnitus. Historically, Ginkgo biloba has been recommended by herbalists for various circulatory and neurological ailments for centuries.

Scientifically, the evidence for Ginkgoside or Ginkgo biloba extract in the treatment of tinnitus is mixed and generally not robust. Some small randomized controlled trials and meta-analyses have suggested a mild benefit in reducing the severity or perception of tinnitus, particularly in cases of recent-onset tinnitus. However, larger, high-quality studies—such as the GATE (Ginkgo for the Treatment of Tinnitus) trial—have failed to demonstrate a significant difference between Ginkgo and placebo. Major clinical guidelines currently do not recommend Ginkgo for tinnitus as standard therapy due to insufficient and inconsistent evidence.

In summary, while Ginkgoside's use for tinnitus is historically rooted and still popular in some traditional and complementary medicine practices, scientific validation is weak, and efficacy remains unproven according to current rigorous clinical research.

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