Evidence supporting the use of: Bitter Melon
For the health condition: Triglycerides (high)

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Bitter melon (Momordica charantia) is traditionally used in various cultures for its purported benefits in managing blood sugar and metabolic health. There is some scientific interest in its potential effects on lipid profiles, including triglyceride levels. Preclinical studies in animal models have shown that bitter melon extracts can reduce serum triglyceride levels, possibly due to its high content of bioactive compounds such as charantin, polypeptide-p, and various saponins. These compounds may exert lipid-lowering effects by modulating lipid metabolism, enhancing fatty acid oxidation, and improving insulin sensitivity.

However, evidence in humans remains limited and inconsistent. A few small human trials have reported modest reductions in triglyceride levels after supplementation with bitter melon, but these studies often have methodological weaknesses such as small sample sizes, short durations, or lack of blinding. Systematic reviews and meta-analyses have concluded that while there is some promise, the current clinical evidence is insufficient to strongly support the use of bitter melon for lowering triglycerides in humans. The ingredient is better studied and more consistently effective for blood glucose regulation than for lipid lowering. Therefore, while there is a scientific rationale and some preliminary evidence, the overall support is weak and more robust, larger-scale human trials are needed.

More about Bitter Melon
More about Triglycerides (high)

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Products containing Bitter Melon

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