Evidence supporting the use of: Hydroxycinnamic acid
For the health condition: Triglycerides (high)
Synopsis
Source of validity: Scientific
Rating (out of 5): 2
Hydroxycinnamic acids are a group of polyphenolic compounds found in various plant-based foods, such as coffee, whole grains, fruits, and vegetables. The main compounds in this group include caffeic acid, ferulic acid, and p-coumaric acid. There is some scientific evidence suggesting that hydroxycinnamic acids may influence lipid metabolism, including triglyceride levels. Several animal and in vitro studies indicate that these compounds can exert lipid-lowering effects by modulating enzymes involved in lipid synthesis and breakdown, and by exerting antioxidant activity that may protect against lipid peroxidation.
Some small human studies and clinical trials have investigated foods rich in hydroxycinnamic acids (such as coffee or whole grains) and noted modest reductions in triglyceride levels, but results are inconsistent and often confounded by other dietary factors. For example, a meta-analysis of coffee consumption indicates potential benefits for lipid profiles, but isolating the effect of hydroxycinnamic acids specifically is challenging. The direct supplementation of isolated hydroxycinnamic acids for lowering triglycerides in humans has not been extensively studied, and high-quality, large-scale clinical trials are lacking.
In summary, while there is a plausible biological rationale and some preliminary scientific evidence for hydroxycinnamic acids supporting healthy triglyceride levels, the evidence is limited and not robust. Therefore, the overall rating for scientific support is low.
More about Hydroxycinnamic acid
More about Triglycerides (high)
Other ingredients used for Triglycerides (high)
akkermansia muciniphilaalgal oil
alpha-linolenic acid (ALA)
anchovies
anthocyanins
apple
arjun tree
artichoke
ashwagandha
astaxanthin
banaba
beet
berberine
bergamot
Beta-Glucan
black currant
black garlic
sesame
black tea
blueberry
broccoli
calamari oil
canola oil
catechins
chia seed
chokeberry
choline
coleus forskohlii
conjugated linoleic acid (CLA)
cordyceps
daidzin
DHA (docosahexaeonic acid)
diallyl disulfide (DADS)
diallyl trisulfide (DATS)
DPA (docosapentaenoic acid)
EPA (eicosapentaenoic acid)
epigallocatechin gallate (EGCG)
fish protein
flaxseed
fruit and vegetable blend (proprietary)
genistein
genistin
glucomannan
grape
grapefruit
green tea
guar gum
guggul
hawthorn
hesperetin
hibiscus
inulin
knotweed
kale
krill oil
kudzu
l-carnitine
l-taurine
lecithin
lignans
linoleic acid (LA)
lycopene
mackerel
magnesium
maqui berry
matcha
naringin
niacin (vitamin B3)
oat
oleanolic acid
oleic acid
olive
omega-3 fatty acids
omega-7 fatty acids
omega-9 fatty acids
oyster mushroom
palmitoleic acid
pantethine
perilla
phospholipids
pine bark
plant sterols
pomegranate
pomelo
quercetin
quinoa
red yeast rice
resveratrol
safflower oil
sardines
silymarin
black ginger
soybean
spirulina
sterols
stevia
strawberry
tocotrienols
tomato
trans-pterostilbene
trimethylglycine (TMG)
almond fruit
ubiquinol
vegetable and fruit blend (proprietary)
vitamin C
mulberry
zinc
β-nicotinamide mononucleotide (NMN)
jiaogulan
lingzhi
sunflower
yerba mate
goji berry
amaranth
kidney beans
cocoa
AMP-activated protein kinase (AMPK)
ashitaba
3-(4-hydroxy-3-methoxyphenyl)prop-2-enoic acid
4-hydroxyisoleucine
Arjuna
Aronia melanocarpa
Avocado
Ascophyllum nodosum
Alpha-Lipoic Acid
Astragaloside
Adzuki bean
Ampelopsin
Alpha phytosterol
Algal protein
Arjunic Acid
Algalin
Alliin
Arabinoxylan
Argan nut oil
alpha Methyl Tetradecylthioacetic Acid
Arjunolic acid
Buglossoides arvensis
Brutieridin
Brassica
Brazil nut
Buckwheat
Bottle gourd
California chia
Cardarine
Chitosan
Camelina Oil
Cod Liver Oil
Coriander
Cashew
Cyanidin
chlorogenic acid
Chinese Fleeceflower
Cynarin
Cruciferous
Capsiate
Chitin-Glucan Complex
Calanus finmarchicus
Crocetin
corosolic acid
Crypthecodinium
Carnosic acid
Docosahexaenoic Acid
Danshen
Daidzein
Dragon Fruit
Diosgenin
Eriocitrin
Emblicanin
Eicosatetraenoic acid
Eicosapentaenoic Acid
Echium
Ecklonia
Flammulina velutipes
Isoflavones
Pistachio
Soy Protein
walnut
Other health conditions supported by Hydroxycinnamic acid
Cancer (prevention)Cardiovascular Disease
Cholesterol (high)
Diabetes
Digestion (poor)
Fatty Liver Disease
Free Radical Damage
Hypertension
Inflammation
Triglycerides (high)
Ulcers
Wounds and Sores