Evidence supporting the use of: Lignan (unspecified)
For the health condition: Triglycerides (high)

Links: Go back one page, Tool main page, Ingredients list, Health conditions list, Body systems list

Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Lignans are a group of polyphenolic compounds found in plants, especially seeds such as flaxseed. Some scientific evidence suggests that lignans may have a beneficial effect on lipid profiles, including triglyceride levels. Most of the available research focuses on flaxseed lignans, particularly secoisolariciresinol diglucoside (SDG). Clinical studies have shown that whole flaxseed or flaxseed extracts, which are rich in lignans and fiber, can modestly reduce serum triglyceride levels, particularly in populations with elevated lipids or metabolic syndrome. The lipid-modulating effects are thought to result from a combination of mechanisms, including improved insulin sensitivity, modulation of hepatic lipid metabolism, and mild estrogenic effects of enterolignans (the mammalian metabolites of lignans).

However, the evidence is neither robust nor consistent. Many studies are small, use whole flaxseed (which contains other bioactive compounds), or show only modest improvements. Isolated lignan supplements have been less well-studied. Systematic reviews and meta-analyses generally report a small but statistically significant reduction in triglyceride levels with flaxseed supplementation, but it is difficult to attribute the effect solely to lignans versus other flax components (like fiber or alpha-linolenic acid).

In summary, there is some scientific evidence, though not strong, that dietary lignans—primarily from flaxseed—may help lower high triglycerides. The evidence supporting the use of isolated lignans for this specific purpose is limited.

More about Lignan (unspecified)
More about Triglycerides (high)

Other ingredients used for Triglycerides (high)

akkermansia muciniphila
algal oil
alpha-linolenic acid (ALA)
anchovies
anthocyanins
apple
arjun tree
artichoke
ashwagandha
astaxanthin
banaba
beet
berberine
bergamot
Beta-Glucan
black currant
black garlic
sesame
black tea
blueberry
broccoli
calamari oil
canola oil
catechins
chia seed
chokeberry
choline
coleus forskohlii
conjugated linoleic acid (CLA)
cordyceps
daidzin
DHA (docosahexaeonic acid)
diallyl disulfide (DADS)
diallyl trisulfide (DATS)
DPA (docosapentaenoic acid)
EPA (eicosapentaenoic acid)
epigallocatechin gallate (EGCG)
fish protein
flaxseed
fruit and vegetable blend (proprietary)
genistein
genistin
glucomannan
grape
grapefruit
green tea
guar gum
guggul
hawthorn
hesperetin
hibiscus
inulin
knotweed
kale
krill oil
kudzu
l-carnitine
l-taurine
lecithin
lignans
linoleic acid (LA)
lycopene
mackerel
magnesium
maqui berry
matcha
naringin
niacin (vitamin B3)
oat
oleanolic acid
oleic acid
olive
omega-3 fatty acids
omega-7 fatty acids
omega-9 fatty acids
oyster mushroom
palmitoleic acid
pantethine
perilla
phospholipids
pine bark
plant sterols
pomegranate
pomelo
quercetin
quinoa
red yeast rice
resveratrol
safflower oil
sardines
silymarin
black ginger
soybean
spirulina
sterols
stevia
strawberry
tocotrienols
tomato
trans-pterostilbene
trimethylglycine (TMG)
almond fruit
ubiquinol
vegetable and fruit blend (proprietary)
vitamin C
mulberry
zinc
β-nicotinamide mononucleotide (NMN)
jiaogulan
lingzhi
sunflower
yerba mate
goji berry
amaranth
kidney beans
cocoa
AMP-activated protein kinase (AMPK)
ashitaba
3-(4-hydroxy-3-methoxyphenyl)prop-2-enoic acid
4-hydroxyisoleucine
Arjuna
Aronia melanocarpa
Avocado
Ascophyllum nodosum
Alpha-Lipoic Acid
Astragaloside
Adzuki bean
Ampelopsin
Alpha phytosterol
Algal protein
Arjunic Acid
Algalin
Alliin
Arabinoxylan
Argan nut oil
alpha Methyl Tetradecylthioacetic Acid
Arjunolic acid
Buglossoides arvensis
Brutieridin
Brassica
Brazil nut
Buckwheat
Bottle gourd
California chia
Cardarine
Chitosan
Camelina Oil
Cod Liver Oil
Coriander
Cashew
Cyanidin
chlorogenic acid
Chinese Fleeceflower
Cynarin
Cruciferous
Capsiate
Chitin-Glucan Complex
Calanus finmarchicus
Crocetin
corosolic acid
Crypthecodinium
Carnosic acid
Docosahexaenoic Acid
Danshen
Daidzein
Dragon Fruit
Diosgenin
Eriocitrin
Emblicanin
Eicosatetraenoic acid
Eicosapentaenoic Acid
Echium
Ecklonia
Flammulina velutipes
Isoflavones
Pistachio
Soy Protein
walnut

Products containing Lignan (unspecified)

We currently have no products on Vitabase that contain this ingredient.