Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Linoleic acid (LA), an essential omega-6 polyunsaturated fatty acid, has been investigated for its effects on lipid profiles, including triglyceride levels. Several epidemiological and clinical studies suggest that dietary intake of LA, typically through vegetable oils (such as safflower, sunflower, and corn oil), may help reduce serum triglycerides when replacing saturated fats in the diet. The primary mechanism is thought to involve enhanced activity of lipoprotein lipase and improved clearance of triglyceride-rich lipoproteins. Meta-analyses have shown that diets higher in polyunsaturated fats, including LA, can modestly lower triglyceride levels compared to diets high in saturated fats.

However, the effect size is generally moderate, and LA is more renowned for its LDL cholesterol-lowering effect than for targeting triglycerides specifically. The American Heart Association recommends replacing saturated fats with polyunsaturated fats (like LA) as part of an overall strategy for cardiovascular risk reduction, which includes lowering triglyceride levels. It is important to note that excessive intake of LA without a balanced omega-3 intake may have pro-inflammatory effects, so recommendations typically focus on overall dietary patterns rather than LA supplementation alone.

In summary, there is moderate scientific evidence supporting the use of linoleic acid to help reduce high triglycerides, primarily when used as a replacement for saturated fats in the context of a heart-healthy diet. Its triglyceride-lowering effect is supported by clinical data, but is less pronounced than its effect on LDL cholesterol.

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Douglas Laboratories Ultra G.L.A. Borage Oil