Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Monacolin K, the primary active compound in red yeast rice, is structurally identical to lovastatin, a prescription statin used to lower cholesterol. The majority of scientific research has focused on Monacolin K's ability to lower LDL cholesterol rather than triglycerides. However, some studies have reported modest reductions in triglyceride levels as a secondary outcome in participants taking red yeast rice or Monacolin K supplements. For example, meta-analyses and randomized controlled trials have noted decreases in triglycerides, but these effects tend to be less pronounced compared to their impact on LDL cholesterol.

The proposed mechanism is similar to statins, which inhibit HMG-CoA reductase in the liver, thereby reducing cholesterol synthesis and, to a lesser extent, triglyceride levels. While there is scientific evidence supporting Monacolin K's effect on triglycerides, it is generally considered moderate; the primary clinical benefit remains LDL reduction. Guidelines and reviews, including those from the European Atherosclerosis Society, recognize the LDL-lowering effect but advise caution regarding supplement quality and potential side effects. Overall, the use of Monacolin K for high triglycerides is supported by scientific evidence, but its efficacy is less robust than for cholesterol management.

More about Monacolin
More about Triglycerides (high)

Other ingredients used for Triglycerides (high)

Akkermansia muciniphila
algal oil
alpha-linolenic acid (ALA)
anchovies
anthocyanins
apple
arjun tree
artichoke
ashwagandha
astaxanthin
banaba
beet
berberine
bergamot
Beta-Glucan
black currant
black garlic
sesame
black tea
blueberry
broccoli
calamari oil
canola oil
catechins
chia seed
chokeberry
choline
coleus forskohlii
conjugated linoleic acid (CLA)
cordyceps
daidzin
DHA (docosahexaeonic acid)
diallyl disulfide (DADS)
diallyl trisulfide (DATS)
DPA (docosapentaenoic acid)
EPA (eicosapentaenoic acid)
epigallocatechin gallate (EGCG)
fish protein
flaxseed
fruit and vegetable blend (proprietary)
genistein
genistin
glucomannan
grape
grapefruit
green tea
guar gum
guggul
hawthorn
hesperetin
hibiscus
inulin
knotweed
kale
krill oil
kudzu
l-carnitine
L-taurine
lecithin
lignans
linoleic acid (LA)
lycopene
mackerel
magnesium
maqui berry
matcha
naringin
niacin (vitamin B3)
oat
oleanolic acid
oleic acid
olive
omega-3 fatty acids
omega-7 fatty acids
omega-9 fatty acids
oyster mushroom
palmitoleic acid
pantethine
perilla
phospholipids
pine bark
plant sterols
pomegranate
pomelo
quercetin
quinoa
red yeast rice
resveratrol
safflower oil
sardines
silymarin
black ginger
soybean
spirulina
sterols
stevia
strawberry
tocotrienols
tomato
trans-pterostilbene
trimethylglycine (TMG)
Almond fruit
ubiquinol
vegetable and fruit blend (proprietary)
vitamin C
mulberry
zinc
β-nicotinamide mononucleotide (NMN)
jiaogulan
lingzhi
sunflower
yerba mate
goji berry
amaranth
kidney beans
cocoa
AMP-activated protein kinase (AMPK)
ashitaba
3-(4-hydroxy-3-methoxyphenyl)prop-2-enoic acid
4-hydroxyisoleucine
Arjuna
Aronia melanocarpa
Avocado
Ascophyllum nodosum
Alpha-Lipoic Acid
Astragaloside
Adzuki bean
Ampelopsin
Alpha phytosterol
Algal protein
Arjunic Acid
Algalin
Alliin
Arabinoxylan
Argan nut oil
Alpha methyl Tetradecylthioacetic Acid
Arjunolic acid
Buglossoides arvensis
Brutieridin
Brassica
Brazil nut
Buckwheat
Bottle gourd
California chia
Cardarine
Chitosan
Camelina Oil
Cod Liver Oil
Coriander
Cashew
Cyanidin
chlorogenic acid
Chinese Fleeceflower
Cynarin
Cruciferous
Capsiate
Chitin-Glucan Complex
Calanus finmarchicus
Crocetin
corosolic acid
Crypthecodinium
Carnosic acid
Docosahexaenoic Acid
Danshen
Daidzein
Dragon Fruit
Diosgenin
Eriocitrin
Emblicanin
Eicosatetraenoic acid
Eicosapentaenoic Acid
Echium
Ecklonia
Fucosterol
Fo-Ti
Fish
Flavanones
Fucoxanthin
Flavanols
Flammulina velutipes
Ginsenosides
Gypenoside
Guggulsterones
Glucoraphanin
Horse Gram
Hydroxycinnamic acid
Hydroxytyrosol
Irvingia gabonensis
Isoflavones
Jicama
Konjac
Kiwi
Kaempferol
Kutkins
Kamut
Kaempferide
Kuding tea
Linseed Oil
Legume protein
Lentil
Lupin
Monacolin
Mortierella alpina
Maslinic Acid
Mangiferin
Myricetin
Macadamia
Millet
Monounsaturated Fat
Marine fat
Mate
Naringenin
Nobiletin
Nannochloropsis
Oleuropein
Oolong Tea
Osthole
Puerarin
Phaeophyceae
Plankton
Polychitosamine
Piceid
Polydatin
Polyunsaturated Fat
Pleurotus eryngii
Pu-Er Tea
Purple Tea
Punicalagins
Pinolenic acid
Phytoestrogens
Pistachio
Polymethoxylated flavones
Plukenetia volubilis
Red Yeast
Rooibos
Rosa Roxburghii
Rapeseed Oil
Schizochytrium Oil
Soy
Schizochytrium
Sitosterol
Salmon Oil
Salidroside
Silybin
Salvianolic acid
Salba Oil
Salacia
Soy Protein
Schisandrins
Sesamolin
Shilajit
Stearidonic acid
Sacha Inchi
S-allylcysteine
Sesamin
Stilbenoid
Tagatose
Tetradecylthioacetic acid
Thylakoid
Taxifolin
Tangeretin
Tejocote
Tanshinone
Taurine
Theaflavin
Theabrownin
Ursolic Acid
vegetable oil
Vegetable Protein
Vine tea
Wakame
walnut

Other health conditions supported by Monacolin

Arteriosclerosis
Cardiovascular Disease
Cholesterol (high)
Circulation (poor)
Metabolic Syndrome
Triglycerides (high)

Products containing Monacolin

We currently have no products on Vitabase that contain this ingredient.