Evidence supporting the use of: Nicotinamide Mononucleotide
For the health condition: Triglycerides (high)

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Nicotinamide Mononucleotide (NMN) is a precursor to nicotinamide adenine dinucleotide (NAD+), a molecule involved in energy metabolism and cellular health. Elevated triglycerides are a risk factor for cardiovascular disease, and some preclinical studies suggest that boosting NAD+ levels via NMN supplementation may positively affect lipid metabolism. In animal studies, NMN administration has been associated with improved lipid profiles, including reductions in triglyceride levels, likely due to enhanced mitochondrial function and improved insulin sensitivity.

However, human clinical data are currently limited. A few small human trials have explored NMN’s safety and metabolic effects, but robust, direct evidence for significant triglyceride lowering in humans is lacking. Most available human studies focus on NMN’s effects on insulin sensitivity, glucose tolerance, or general metabolic health, with triglyceride effects being a secondary or incidental outcome. Thus, while there is a plausible biological mechanism and some encouraging animal data, the clinical evidence for NMN as a treatment for high triglycerides is weak at this time.

In summary, NMN is being investigated for various metabolic benefits, including potential improvements in triglyceride levels. However, current scientific validation is limited, and its use for this specific condition should be considered experimental until larger, well-controlled human studies are completed.

More about Nicotinamide Mononucleotide
More about Triglycerides (high)

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Products containing Nicotinamide Mononucleotide

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