Evidence supporting the use of: Omega-3 fatty acids
For the health condition: Triglycerides (high)

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Synopsis

Source of validity: Scientific
Rating (out of 5): 5

Omega-3 fatty acids, particularly the forms eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) found in fish oil, have strong scientific validation for use in lowering high triglyceride levels. Numerous randomized controlled trials and meta-analyses have demonstrated that supplementation with omega-3 fatty acids can significantly reduce triglyceride concentrations in individuals with hypertriglyceridemia. The mechanism is thought to involve decreased hepatic synthesis of triglycerides and increased clearance of very-low-density lipoprotein (VLDL) particles from the bloodstream. Prescription-strength omega-3 products (such as icosapent ethyl and omega-3-acid ethyl esters) are approved by the FDA for treating severe hypertriglyceridemia (≥500 mg/dL). Clinical guidelines from major organizations, including the American Heart Association and the Endocrine Society, recommend omega-3 fatty acid therapy as an adjunct to diet and lifestyle changes for patients with significantly elevated triglyceride levels. Typical reductions in triglycerides range from 20-50% depending on dose (usually 2-4 grams of EPA/DHA daily) and baseline triglyceride level. While over-the-counter fish oil supplements may have some effect, pharmaceutical-grade preparations are standardized and more effective for medical use. Overall, the evidence base for omega-3 fatty acids in the management of high triglycerides is robust, and their use is supported by both regulatory approval and clinical practice guidelines.

More about omega-3 fatty acids
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Other ingredients used for Triglycerides (high)

Akkermansia muciniphila
algal oil
alpha-linolenic acid (ALA)
anchovies
anthocyanins
apple
arjun tree
artichoke
ashwagandha
astaxanthin
banaba
beet
berberine
bergamot
Beta-Glucan
black currant
black garlic
sesame
black tea
blueberry
broccoli
calamari oil
canola oil
catechins
chia seed
chokeberry
choline
coleus forskohlii
conjugated linoleic acid (CLA)
cordyceps
daidzin
DHA (docosahexaeonic acid)
diallyl disulfide (DADS)
diallyl trisulfide (DATS)
DPA (docosapentaenoic acid)
EPA (eicosapentaenoic acid)
epigallocatechin gallate (EGCG)
fish protein
flaxseed
fruit and vegetable blend (proprietary)
genistein
genistin
glucomannan
grape
grapefruit
green tea
guar gum
guggul
hawthorn
hesperetin
hibiscus
inulin
knotweed
kale
krill oil
kudzu
l-carnitine
L-taurine
lecithin
lignans
linoleic acid (LA)
lycopene
mackerel
magnesium
maqui berry
matcha
naringin
niacin (vitamin B3)
oat
oleanolic acid
oleic acid
olive
omega-3 fatty acids
omega-7 fatty acids
omega-9 fatty acids
oyster mushroom
palmitoleic acid
pantethine
perilla
phospholipids
pine bark
plant sterols
pomegranate
pomelo
quercetin
quinoa
red yeast rice
resveratrol
safflower oil
sardines
silymarin
black ginger
soybean
spirulina
sterols
stevia
strawberry
tocotrienols
tomato
trans-pterostilbene
trimethylglycine (TMG)
Almond fruit
ubiquinol
vegetable and fruit blend (proprietary)
vitamin C
mulberry
zinc
β-nicotinamide mononucleotide (NMN)
jiaogulan
lingzhi
sunflower
yerba mate
goji berry
amaranth
kidney beans
cocoa
AMP-activated protein kinase (AMPK)
ashitaba
3-(4-hydroxy-3-methoxyphenyl)prop-2-enoic acid
4-hydroxyisoleucine
Arjuna
Aronia melanocarpa
Avocado
Ascophyllum nodosum
Alpha-Lipoic Acid
Astragaloside
Adzuki bean
Ampelopsin
Alpha phytosterol
Algal protein
Arjunic Acid
Algalin
Alliin
Arabinoxylan
Argan nut oil
Alpha methyl Tetradecylthioacetic Acid
Arjunolic acid
Buglossoides arvensis
Brutieridin
Brassica
Brazil nut
Buckwheat
Bottle gourd
California chia
Cardarine
Chitosan
Camelina Oil
Cod Liver Oil
Coriander
Cashew
Cyanidin
chlorogenic acid
Chinese Fleeceflower
Cynarin
Cruciferous
Capsiate
Chitin-Glucan Complex
Calanus finmarchicus
Crocetin
corosolic acid
Crypthecodinium
Carnosic acid
Docosahexaenoic Acid
Danshen
Daidzein
Dragon Fruit
Diosgenin
Eriocitrin
Emblicanin
Eicosatetraenoic acid
Eicosapentaenoic Acid
Echium
Ecklonia
Fucosterol
Fo-Ti
Fish
Flavanones
Fucoxanthin
Flavanols
Flammulina velutipes
Ginsenosides
Gypenoside
Guggulsterones
Glucoraphanin
Horse Gram
Hydroxycinnamic acid
Hydroxytyrosol
Irvingia gabonensis
Isoflavones
Jicama
Konjac
Kiwi
Kaempferol
Kutkins
Kamut
Kaempferide
Kuding tea
Linseed Oil
Legume protein
Lentil
Lupin
Monacolin
Mortierella alpina
Maslinic Acid
Mangiferin
Myricetin
Macadamia
Millet
Monounsaturated Fat
Marine fat
Mate
Naringenin
Nobiletin
Nannochloropsis
Oleuropein
Oolong Tea
Osthole
Puerarin
Phaeophyceae
Plankton
Polychitosamine
Piceid
Polydatin
Polyunsaturated Fat
Pleurotus eryngii
Pu-Er Tea
Purple Tea
Punicalagins
Pinolenic acid
Phytoestrogens
Pistachio
Polymethoxylated flavones
Plukenetia volubilis
Red Yeast
Rooibos
Rosa Roxburghii
Rapeseed Oil
Schizochytrium Oil
Soy
Schizochytrium
Sitosterol
Salmon Oil
Salidroside
Silybin
Salvianolic acid
Salba Oil
Salacia
Soy Protein
Schisandrins
Sesamolin
Shilajit
Stearidonic acid
Sacha Inchi
S-allylcysteine
Sesamin
Stilbenoid
Tagatose
Tetradecylthioacetic acid
Thylakoid
Taxifolin
Tangeretin
Tejocote
Tanshinone
Taurine
Theaflavin
Theabrownin
Ursolic Acid
vegetable oil
Vegetable Protein
Vine tea
Wakame
walnut

Other health conditions supported by omega-3 fatty acids

Acne
Acquired Immune Deficiency Syndrome
Addictions (drugs)
Addictions (general remedies for)
Addictions (tobacco smoking or chewing)
Aging (prevention)
Alcoholism
Allergies (food)
Allergies (respiratory)
Alzheimer's Disease
Angina
Anorexia
Anxiety
Anxiety Disorders
Apathy
Arrhythmia
Arteriosclerosis
Anger (excessive)
Arthritis
Asthma
Athletic and Exercise Aids
Attention Deficit Disorder
Autism
Autoimmune Disorders
Backache
Bipolar Mood Disorder
Birth Defects (prevention)
Blood Clots (prevention of)
Bloodshot Eyes
Body Building
Broken Bones
Bulimia
Cancer (natural therapy for)
Cancer (prevention)
Cancer Treatment (reducing side effects)
Canker Sores
Cardiovascular Disease
Cartilage Damage
Cholesterol (high)
Cholesterol (low)
Chronic Obstructive Pulmonary Disorder
Circulation (poor)
Circulation (to the brain)
Concentration (poor)
Concussions
Confusion
Congestive Heart Failure
Dementia
Depression
Diabetes
Dysmenorrhea
Eczema
Emotional Sensitivity
Endometriosis
Epilepsy
Exercise
Eye Problems
Eyes (red or itching)
Eyesight (poor)
Fat Metabolism (poor)
Fatigue
Fatty Liver Disease
Fibrosis
Free Radical Damage
Glaucoma
Gout
Hair (loss or thinning)
Hair Care (general)
Hashimoto's Disease
Hearing Loss
Heart (weakness)
Heart Fibrillation or Palpitations
Hepatitis
Hypertension
Infertility
Inflammation
Inflammatory Bowel Disorders
Irritability
Lou Gehrig's Disease
Lupus
Macular Degeneration
Memory and Brain Function
Menopause
Metabolic Syndrome
Migraine
Muscular Dystrophy
Nerve Damage
Neuralgia and Neuritis
Numbness
Osteoporosis
Parkinson's Disease
Peripheral Neuropathy
Pets (supplements for)
PMS Type D
PMS Type P
PMS Type S
Polyps
Post Partum Depression
Post Partum Weakness
Pregnancy (herbs and supplements for)
Psoriasis
Raynaud's Disease
Rheumatoid Arthritis
Rosacea
Schizophrenia
Seasonal Affective Disorder
Seborrhea
Seizures
Senility
Sickle Cell Anemia
Skin (dry and/or flaky)
Skin Care (general)
Spinal Disks
Strokes
Surgery (healing from)
Surgery (preparation for)
Thinking (cloudy)
Thrombosis
Triglycerides (high)
Triglycerides (low)
Vaginal Dryness