Evidence supporting the use of: Pinolenic acid
For the health condition: Triglycerides (high)
Synopsis
Source of validity: Scientific
Rating (out of 5): 2
Pinolenic acid, a polyunsaturated fatty acid found primarily in pine nut oil (notably from Korean pine nuts), has garnered interest for its potential lipid-lowering effects, particularly on triglycerides. Several small-scale human clinical trials and animal studies have investigated its impact on lipid profiles. Research indicates that pinolenic acid may help decrease serum triglyceride levels, possibly by enhancing hepatic fatty acid oxidation and modulating enzymes involved in lipid metabolism. For example, a 2008 double-blind, placebo-controlled study published in Lipids in Health and Disease observed a modest reduction in triglycerides among overweight women consuming Korean pine nut oil. Additionally, animal studies have shown that pinolenic acid supplementation can lead to improvements in lipid parameters, including triglycerides, through mechanisms such as upregulation of peroxisome proliferator-activated receptor alpha (PPAR-α) activity. However, the total body of evidence remains limited, with relatively few high-quality, large-scale human trials. The magnitude of triglyceride-lowering appears moderate at best, and there is no consensus on optimal dosage or long-term effects. While the early results are promising and suggest a scientific basis for pinolenic acid’s use in supporting healthy triglyceride levels, the overall quality and quantity of evidence are currently insufficient for strong recommendations. Thus, pinolenic acid is best considered an adjunct, rather than a primary therapy, for individuals seeking to manage elevated triglycerides.
Other ingredients used for Triglycerides (high)
akkermansia muciniphilaalgal oil
alpha-linolenic acid (ALA)
anchovies
anthocyanins
apple
arjun tree
artichoke
ashwagandha
astaxanthin
banaba
beet
berberine
bergamot
Beta-Glucan
black currant
black garlic
sesame
black tea
blueberry
broccoli
calamari oil
canola oil
catechins
chia seed
chokeberry
choline
coleus forskohlii
conjugated linoleic acid (CLA)
cordyceps
daidzin
DHA (docosahexaeonic acid)
diallyl disulfide (DADS)
diallyl trisulfide (DATS)
DPA (docosapentaenoic acid)
EPA (eicosapentaenoic acid)
epigallocatechin gallate (EGCG)
fish protein
flaxseed
fruit and vegetable blend (proprietary)
genistein
genistin
glucomannan
grape
grapefruit
green tea
guar gum
guggul
hawthorn
hesperetin
hibiscus
inulin
knotweed
kale
krill oil
kudzu
l-carnitine
l-taurine
lecithin
lignans
linoleic acid (LA)
lycopene
mackerel
magnesium
maqui berry
matcha
naringin
niacin (vitamin B3)
oat
oleanolic acid
oleic acid
olive
omega-3 fatty acids
omega-7 fatty acids
omega-9 fatty acids
oyster mushroom
palmitoleic acid
pantethine
perilla
phospholipids
pine bark
plant sterols
pomegranate
pomelo
quercetin
quinoa
red yeast rice
resveratrol
safflower oil
sardines
silymarin
black ginger
soybean
spirulina
sterols
stevia
strawberry
tocotrienols
tomato
trans-pterostilbene
trimethylglycine (TMG)
almond fruit
ubiquinol
vegetable and fruit blend (proprietary)
vitamin C
mulberry
zinc
β-nicotinamide mononucleotide (NMN)
jiaogulan
lingzhi
sunflower
yerba mate
goji berry
amaranth
kidney beans
cocoa
AMP-activated protein kinase (AMPK)
ashitaba
3-(4-hydroxy-3-methoxyphenyl)prop-2-enoic acid
4-hydroxyisoleucine
Arjuna
Aronia melanocarpa
Avocado
Ascophyllum nodosum
Alpha-Lipoic Acid
Astragaloside
Adzuki bean
Ampelopsin
Alpha phytosterol
Algal protein
Arjunic Acid
Algalin
Alliin
Arabinoxylan
Argan nut oil
alpha Methyl Tetradecylthioacetic Acid
Arjunolic acid
Buglossoides arvensis
Brutieridin
Brassica
Brazil nut
Buckwheat
Bottle gourd
California chia
Cardarine
Chitosan
Camelina Oil
Cod Liver Oil
Coriander
Cashew
Cyanidin
chlorogenic acid
Chinese Fleeceflower
Cynarin
Cruciferous
Capsiate
Chitin-Glucan Complex
Calanus finmarchicus
Crocetin
corosolic acid
Crypthecodinium
Carnosic acid
Docosahexaenoic Acid
Danshen
Daidzein
Dragon Fruit
Diosgenin
Eriocitrin
Emblicanin
Eicosatetraenoic acid
Eicosapentaenoic Acid
Echium
Ecklonia
Flammulina velutipes
Isoflavones
Pistachio
Soy Protein
walnut
Other health conditions supported by Pinolenic acid
Appetite (deficient)Cholesterol (high)
Fat Metabolism (poor)
Triglycerides (high)