Evidence supporting the use of: Proanthocyanidin
For the health condition: Triglycerides (high)
Synopsis
Source of validity: Scientific
Rating (out of 5): 2
Proanthocyanidins are a class of polyphenolic compounds found in many plants, especially in fruits like grapes, apples, and berries. There is some scientific interest in their potential to support healthy lipid profiles, including triglyceride levels. Animal studies and a limited number of small human trials suggest that proanthocyanidins may have lipid-lowering effects, possibly due to their antioxidant properties, modulation of lipid metabolism, and improvement in insulin sensitivity. For example, a few randomized controlled trials using grape seed extract (rich in proanthocyanidins) have reported modest reductions in triglyceride levels in subjects with metabolic syndrome or hyperlipidemia. However, these studies often have small sample sizes, short durations, and sometimes use combinations with other bioactive compounds, making it difficult to attribute effects solely to proanthocyanidins. Systematic reviews note the need for larger, well-designed trials to confirm efficacy and determine optimal dosing. Currently, while there is some mechanistic rationale and preliminary clinical data, the overall evidence remains limited and inconsistent. Therefore, proanthocyanidins cannot be considered a first-line or well-established option for the management of high triglycerides based on current evidence.
Other ingredients used for Triglycerides (high)
akkermansia muciniphilaalgal oil
alpha-linolenic acid (ALA)
anchovies
anthocyanins
apple
arjun tree
artichoke
ashwagandha
astaxanthin
banaba
beet
berberine
bergamot
Beta-Glucan
black currant
black garlic
sesame
black tea
blueberry
broccoli
calamari oil
canola oil
catechins
chia seed
chokeberry
choline
coleus forskohlii
conjugated linoleic acid (CLA)
cordyceps
daidzin
DHA (docosahexaeonic acid)
diallyl disulfide (DADS)
diallyl trisulfide (DATS)
DPA (docosapentaenoic acid)
EPA (eicosapentaenoic acid)
epigallocatechin gallate (EGCG)
fish protein
flaxseed
fruit and vegetable blend (proprietary)
genistein
genistin
glucomannan
grape
grapefruit
green tea
guar gum
guggul
hawthorn
hesperetin
hibiscus
inulin
knotweed
kale
krill oil
kudzu
l-carnitine
l-taurine
lecithin
lignans
linoleic acid (LA)
lycopene
mackerel
magnesium
maqui berry
matcha
naringin
niacin (vitamin B3)
oat
oleanolic acid
oleic acid
olive
omega-3 fatty acids
omega-7 fatty acids
omega-9 fatty acids
oyster mushroom
palmitoleic acid
pantethine
perilla
phospholipids
pine bark
plant sterols
pomegranate
pomelo
quercetin
quinoa
red yeast rice
resveratrol
safflower oil
sardines
silymarin
black ginger
soybean
spirulina
sterols
stevia
strawberry
tocotrienols
tomato
trans-pterostilbene
trimethylglycine (TMG)
almond fruit
ubiquinol
vegetable and fruit blend (proprietary)
vitamin C
mulberry
zinc
β-nicotinamide mononucleotide (NMN)
jiaogulan
lingzhi
sunflower
yerba mate
goji berry
amaranth
kidney beans
cocoa
AMP-activated protein kinase (AMPK)
ashitaba
3-(4-hydroxy-3-methoxyphenyl)prop-2-enoic acid
4-hydroxyisoleucine
Arjuna
Aronia melanocarpa
Avocado
Ascophyllum nodosum
Alpha-Lipoic Acid
Astragaloside
Adzuki bean
Ampelopsin
Alpha phytosterol
Algal protein
Arjunic Acid
Algalin
Alliin
Arabinoxylan
Argan nut oil
alpha Methyl Tetradecylthioacetic Acid
Arjunolic acid
Buglossoides arvensis
Brutieridin
Brassica
Brazil nut
Buckwheat
Bottle gourd
California chia
Cardarine
Chitosan
Camelina Oil
Cod Liver Oil
Coriander
Cashew
Cyanidin
chlorogenic acid
Chinese Fleeceflower
Cynarin
Cruciferous
Capsiate
Chitin-Glucan Complex
Calanus finmarchicus
Crocetin
corosolic acid
Crypthecodinium
Carnosic acid
Docosahexaenoic Acid
Danshen
Daidzein
Dragon Fruit
Diosgenin
Eriocitrin
Emblicanin
Eicosatetraenoic acid
Eicosapentaenoic Acid
Echium
Ecklonia
Flammulina velutipes
Isoflavones
Pistachio
Soy Protein
walnut
Other health conditions supported by Proanthocyanidin
Cancer (prevention)Cardiovascular Disease
Cholesterol (high)
Circulation (poor)
Diabetes
Diabetic Retinopathy
Edema
Free Radical Damage
Gingivitis
Hypertension
Inflammation
Osteoporosis
Skin Care (general)
Triglycerides (high)
Ulcers
Urinary Tract Infections
Varicose Veins
Wounds and Sores
Wrinkles