Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Stearidonic acid (SDA) is an omega-3 fatty acid found in certain plant oils, such as echium and hemp seed oil. Its use to support or treat high triglyceride levels is grounded in the fact that SDA is a metabolic precursor to eicosapentaenoic acid (EPA), a long-chain omega-3 fatty acid known to reduce triglyceride levels. However, the evidence supporting SDA specifically for hypertriglyceridemia is limited and less robust compared to EPA or docosahexaenoic acid (DHA).

Clinical trials examining SDA supplementation have demonstrated that it can increase EPA levels in the blood, but this conversion is less efficient than consuming preformed EPA. Some small human studies and animal models have suggested that SDA may have a modest triglyceride-lowering effect, but these effects are generally weaker than what is observed with fish oil-derived EPA and DHA. For example, a 2008 study in The American Journal of Clinical Nutrition showed that SDA-rich oil increased EPA but did not significantly reduce triglycerides in healthy subjects. Reviews and meta-analyses highlight the need for more extensive, controlled trials to determine the efficacy of SDA for this purpose.

In summary, while there is a biochemical rationale and some early research suggesting SDA could modestly impact triglycerides through its conversion to EPA, the direct evidence is limited. SDA is not as well-established or effective as EPA/DHA for lowering triglycerides, so the scientific support for its use in this context is weak to moderate.

More about Stearidonic acid
More about Triglycerides (high)

Other ingredients used for Triglycerides (high)

akkermansia muciniphila
algal oil
alpha-linolenic acid (ALA)
anchovies
anthocyanins
apple
arjun tree
artichoke
ashwagandha
astaxanthin
banaba
beet
berberine
bergamot
Beta-Glucan
black currant
black garlic
sesame
black tea
blueberry
broccoli
calamari oil
canola oil
catechins
chia seed
chokeberry
choline
coleus forskohlii
conjugated linoleic acid (CLA)
cordyceps
daidzin
DHA (docosahexaeonic acid)
diallyl disulfide (DADS)
diallyl trisulfide (DATS)
DPA (docosapentaenoic acid)
EPA (eicosapentaenoic acid)
epigallocatechin gallate (EGCG)
fish protein
flaxseed
fruit and vegetable blend (proprietary)
genistein
genistin
glucomannan
grape
grapefruit
green tea
guar gum
guggul
hawthorn
hesperetin
hibiscus
inulin
knotweed
kale
krill oil
kudzu
l-carnitine
l-taurine
lecithin
lignans
linoleic acid (LA)
lycopene
mackerel
magnesium
maqui berry
matcha
naringin
niacin (vitamin B3)
oat
oleanolic acid
oleic acid
olive
omega-3 fatty acids
omega-7 fatty acids
omega-9 fatty acids
oyster mushroom
palmitoleic acid
pantethine
perilla
phospholipids
pine bark
plant sterols
pomegranate
pomelo
quercetin
quinoa
red yeast rice
resveratrol
safflower oil
sardines
silymarin
black ginger
soybean
spirulina
sterols
stevia
strawberry
tocotrienols
tomato
trans-pterostilbene
trimethylglycine (TMG)
almond fruit
ubiquinol
vegetable and fruit blend (proprietary)
vitamin C
mulberry
zinc
β-nicotinamide mononucleotide (NMN)
jiaogulan
lingzhi
sunflower
yerba mate
goji berry
amaranth
kidney beans
cocoa
AMP-activated protein kinase (AMPK)
ashitaba
3-(4-hydroxy-3-methoxyphenyl)prop-2-enoic acid
4-hydroxyisoleucine
Arjuna
Aronia melanocarpa
Avocado
Ascophyllum nodosum
Alpha-Lipoic Acid
Astragaloside
Adzuki bean
Ampelopsin
Alpha phytosterol
Algal protein
Arjunic Acid
Algalin
Alliin
Arabinoxylan
Argan nut oil
alpha Methyl Tetradecylthioacetic Acid
Arjunolic acid
Buglossoides arvensis
Brutieridin
Brassica
Brazil nut
Buckwheat
Bottle gourd
California chia
Cardarine
Chitosan
Camelina Oil
Cod Liver Oil
Coriander
Cashew
Cyanidin
chlorogenic acid
Chinese Fleeceflower
Cynarin
Cruciferous
Capsiate
Chitin-Glucan Complex
Calanus finmarchicus
Crocetin
corosolic acid
Crypthecodinium
Carnosic acid
Docosahexaenoic Acid
Danshen
Daidzein
Dragon Fruit
Diosgenin
Eriocitrin
Emblicanin
Eicosatetraenoic acid
Eicosapentaenoic Acid
Echium
Ecklonia
Flammulina velutipes
Isoflavones
Pistachio
Soy Protein
walnut

Other health conditions supported by Stearidonic acid

Arthritis
Cardiovascular Disease
Cholesterol (high)
Inflammation
Rheumatoid Arthritis
Triglycerides (high)

Products containing Stearidonic acid

We currently have no products on Vitabase that contain this ingredient.