Evidence supporting the use of: Tanshinone
For the health condition: Triglycerides (high)

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Tanshinone is a group of bioactive diterpene compounds derived from the roots of Salvia miltiorrhiza (Danshen), a traditional Chinese medicinal herb. Scientific research over the past two decades has explored the potential lipid-lowering effects of tanshinones, particularly in relation to high triglycerides. Preclinical studies using animal models and cell cultures have demonstrated that tanshinone IIA and related compounds can decrease serum triglyceride levels, likely through mechanisms involving improved lipid metabolism, reduced hepatic lipid synthesis, and enhanced fatty acid oxidation. Some small-scale clinical trials and human observational studies have reported modest reductions in triglycerides among patients with hyperlipidemia or metabolic syndrome treated with Danshen extracts containing tanshinones.

However, the evidence base is limited: most studies are preclinical, with few high-quality randomized controlled trials in humans. The exact dosage, active component, and long-term safety are not well established. Nonetheless, the accumulating laboratory and early clinical data provide a rationale for further investigation. In summary, while there is some scientific validation for the use of tanshinone-containing extracts to support or lower high triglycerides, the quality and quantity of human evidence remain limited, justifying a moderate evidence rating.

More about Tanshinone
More about Triglycerides (high)

Other ingredients used for Triglycerides (high)

3-(4-hydroxy-3-methoxyphenyl)prop-2-enoic acid
4-hydroxyisoleucine
Adzuki bean
Akkermansia muciniphila
algal oil
Algal protein
Algalin
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Almond fruit
Alpha methyl tetradecylthioacetic acid
Alpha phytosterol
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amaranth
AMP-activated protein kinase (AMPK)
ampelopsin
anchovies
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apple
arabinoxylan
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arjun tree
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Arjunolic acid
Aronia melanocarpa
artichoke
Ascophyllum nodosum
ashitaba
ashwagandha
astaxanthin
astragaloside
avocado
banaba
beet
berberine
bergamot
beta-glucan
black currant
black garlic
black ginger
black tea
blueberry
bottle gourd
Brassica
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broccoli
brutieridin
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Buglossoides arvensis
calamari oil
Calanus finmarchicus
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capsiate
cardarine
carnosic acid
cashew
catechins
chia seed
Chinese fleeceflower
Chitin-Glucan Complex
chitosan
chlorogenic acid
chokeberry
choline
cocoa
cod liver oil
Coleus forskohlii
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cordyceps
coriander
corosolic acid
crocetin
cruciferous
Crypthecodinium
cyanidin
cynarin
daidzein
daidzin
danshen
DHA (docosahexaenoic acid)
diallyl disulfide (DADS)
diallyl trisulfide (DATS)
diosgenin
docosahexaenoic Acid
DPA (docosapentaenoic acid)
dragon fruit
Echium
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eicosapentaenoic acid
Eicosatetraenoic acid
emblicanin
EPA (eicosapentaenoic acid)
epigallocatechin gallate (EGCG)
eriocitrin
fish
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flavanols
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fo-ti
fruit and vegetable blend (proprietary)
fucosterol
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genistein
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Ginsenosides
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goji berry
grape
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green tea
guar gum
guggul
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Gypenoside
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hesperetin
hibiscus
horse gram
hydroxycinnamic acid
hydroxytyrosol
inulin
Irvingia gabonensis
isoflavones
jiaogulan
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lupin
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tocotrienols
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ubiquinol
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vegetable and fruit blend (proprietary)
vegetable oil
Vegetable Protein
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vitamin C
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Zinc
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Products containing Tanshinone

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