Evidence supporting the use of: Unsaturated fatty acid
For the health condition: Triglycerides (high)
Synopsis
Source of validity: Scientific
Rating (out of 5): 4
Unsaturated fatty acids, particularly omega-3 polyunsaturated fatty acids (PUFAs) found in fish oil (such as EPA and DHA), have substantial scientific evidence supporting their use in reducing elevated triglyceride levels. Numerous randomized controlled trials and meta-analyses have demonstrated that supplementation with omega-3 fatty acids can significantly lower serum triglyceride concentrations, especially in individuals with hypertriglyceridemia. The mechanism is believed to involve decreased hepatic very-low-density lipoprotein (VLDL) synthesis and increased clearance of triglyceride-rich particles from the bloodstream.
Clinical guidelines, including those from the American Heart Association and the Endocrine Society, recommend the use of prescription-strength omega-3 fatty acids for patients with high triglyceride levels. While monounsaturated fatty acids (like those found in olive oil) and other polyunsaturated fats (like those in vegetable oils) are also associated with improved lipid profiles compared to saturated fats, their effect on triglycerides is less pronounced than that of marine-derived omega-3s.
It is important to note that the triglyceride-lowering effect is dose-dependent, with significant reductions typically observed at daily intakes of 2-4 grams of EPA/DHA. While dietary interventions replacing saturated fats with unsaturated fats are generally beneficial for cardiovascular health, the most robust evidence for triglyceride lowering pertains to omega-3 fatty acid supplementation.
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Other ingredients used for Triglycerides (high)
akkermansia muciniphilaalgal oil
alpha-linolenic acid (ALA)
anchovies
anthocyanins
apple
arjun tree
artichoke
ashwagandha
astaxanthin
banaba
beet
berberine
bergamot
Beta-Glucan
black currant
black garlic
sesame
black tea
blueberry
broccoli
calamari oil
canola oil
catechins
chia seed
chokeberry
choline
coleus forskohlii
conjugated linoleic acid (CLA)
cordyceps
daidzin
DHA (docosahexaeonic acid)
diallyl disulfide (DADS)
diallyl trisulfide (DATS)
DPA (docosapentaenoic acid)
EPA (eicosapentaenoic acid)
epigallocatechin gallate (EGCG)
fish protein
flaxseed
fruit and vegetable blend (proprietary)
genistein
genistin
glucomannan
grape
grapefruit
green tea
guar gum
guggul
hawthorn
hesperetin
hibiscus
inulin
knotweed
kale
krill oil
kudzu
l-carnitine
l-taurine
lecithin
lignans
linoleic acid (LA)
lycopene
mackerel
magnesium
maqui berry
matcha
naringin
niacin (vitamin B3)
oat
oleanolic acid
oleic acid
olive
omega-3 fatty acids
omega-7 fatty acids
omega-9 fatty acids
oyster mushroom
palmitoleic acid
pantethine
perilla
phospholipids
pine bark
plant sterols
pomegranate
pomelo
quercetin
quinoa
red yeast rice
resveratrol
safflower oil
sardines
silymarin
black ginger
soybean
spirulina
sterols
stevia
strawberry
tocotrienols
tomato
trans-pterostilbene
trimethylglycine (TMG)
almond fruit
ubiquinol
vegetable and fruit blend (proprietary)
vitamin C
mulberry
zinc
β-nicotinamide mononucleotide (NMN)
jiaogulan
lingzhi
sunflower
yerba mate
goji berry
amaranth
kidney beans
cocoa
AMP-activated protein kinase (AMPK)
ashitaba
3-(4-hydroxy-3-methoxyphenyl)prop-2-enoic acid
4-hydroxyisoleucine
Arjuna
Aronia melanocarpa
Avocado
Ascophyllum nodosum
Alpha-Lipoic Acid
Astragaloside
Adzuki bean
Ampelopsin
Alpha phytosterol
Algal protein
Arjunic Acid
Algalin
Alliin
Arabinoxylan
Argan nut oil
alpha Methyl Tetradecylthioacetic Acid
Arjunolic acid
Buglossoides arvensis
Brutieridin
Brassica
Brazil nut
Buckwheat
Bottle gourd
California chia
Cardarine
Chitosan
Camelina Oil
Cod Liver Oil
Coriander
Cashew
Cyanidin
chlorogenic acid
Chinese Fleeceflower
Cynarin
Cruciferous
Capsiate
Chitin-Glucan Complex
Calanus finmarchicus
Crocetin
corosolic acid
Crypthecodinium
Carnosic acid
Docosahexaenoic Acid
Danshen
Daidzein
Dragon Fruit
Diosgenin
Eriocitrin
Emblicanin
Eicosatetraenoic acid
Eicosapentaenoic Acid
Echium
Ecklonia
Fish
Flammulina velutipes
Isoflavones
Pistachio
Soy Protein
walnut
Other health conditions supported by Unsaturated fatty acid
Alzheimer's DiseaseAngina
Arteriosclerosis
Arthritis
Asthma
Blood Clots (prevention of)
Cancer (natural therapy for)
Cancer (prevention)
Cancer Treatment (reducing side effects)
Cardiovascular Disease
Cholesterol (high)
Circulation (poor)
Congestive Heart Failure
Depression
Diabetes
Fatty Liver Disease
Free Radical Damage
Heart (weakness)
Heart Fibrillation or Palpitations
Hypertension
Inflammation
Inflammatory Bowel Disorders
Memory and Brain Function
Metabolic Syndrome
Migraine
Multiple Sclerosis
Osteoporosis
Parkinson's Disease
Peripheral Neuropathy
Psoriasis
Rheumatoid Arthritis
Stress
Strokes
Triglycerides (high)
Wounds and Sores