Evidence supporting the use of: Streptomyces (unspecified)
For the health condition: Tuberculosis

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Synopsis

Source of validity: Scientific
Rating (out of 5): 5

Streptomyces is a genus of Gram-positive bacteria renowned for their role in the natural production of many antibiotics. The most notable connection between Streptomyces and tuberculosis (TB) is the discovery and clinical use of streptomycin, the first effective antibiotic treatment for TB. Streptomyces griseus is the soil bacterium from which streptomycin was originally isolated in 1943 by Selman Waksman and colleagues. Prior to the introduction of streptomycin, TB was a leading cause of death worldwide, and treatments were largely ineffective. Streptomycin’s potent activity against Mycobacterium tuberculosis revolutionized TB therapy and dramatically improved patient outcomes.

Since then, other antibiotics from Streptomyces species (such as kanamycin and capreomycin) have also played important roles in treating drug-resistant TB. The use of antibiotics derived from Streptomyces is fully supported by decades of scientific research, clinical trials, and global medical practice. While resistance and side effects are concerns, these compounds remain essential, particularly for multidrug-resistant cases. The evidence for their use in TB therapy is robust and well-documented in medical literature and treatment guidelines.

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