Alkanet (Alkanna tinctoria) has a long history of traditional use in the management of external ulcerations and wounds. In various traditional medicine systems, especially those of Europe, the Middle East, and South Asia, the root of Alkanet has been applied topically for its purported ability to promote healing, reduce inflammation, and protect against infection. This is largely attributed to its content of naphthoquinone derivatives, such as alkannin, which impart a deep red color to ointments and salves. Historical texts and herbal manuals frequently mention the use of Alkanet root in balms and plasters for chronic ulcers, boils, and other skin afflictions.

However, while there is a clear traditional basis for its use, modern scientific validation is limited. Some in vitro studies have indicated that alkannin and related compounds possess antimicrobial and anti-inflammatory properties, which could theoretically support wound healing. Nevertheless, robust clinical trials or comprehensive studies in humans are lacking. Thus, the evidence supporting Alkanet's use for external ulcerations is predominantly traditional, with some pharmacological rationale but minimal direct scientific proof.