Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Bisabolol, a naturally occurring monocyclic sesquiterpene alcohol found primarily in chamomile (Matricaria recutita), is used in topical formulations for the treatment and support of external ulcerations, such as pressure sores, venous ulcers, and other chronic wounds. Scientific evidence supporting this use is moderate. Bisabolol is well-documented for its anti-inflammatory, antimicrobial, and wound-healing properties. Several in vitro and animal studies have demonstrated that bisabolol can accelerate the wound healing process by modulating inflammatory responses, stimulating fibroblast activity, and promoting collagen synthesis. Its antimicrobial effects help reduce the risk of secondary infection in ulcerated tissues.

Clinical data in humans are more limited but promising. Some randomized controlled trials and observational studies have reported improved healing rates and reduced inflammation when bisabolol-containing creams or ointments are used as adjunctive therapy for skin ulcers. Additionally, bisabolol is recognized for its skin-soothing and barrier-protective effects, making it suitable for application to sensitive, damaged skin. While the body of clinical evidence is not extensive enough to warrant a maximum rating, the mechanistic plausibility and positive results from preliminary studies justify its inclusion in topical treatments for external ulcerations. More large-scale, well-controlled human trials are needed to fully establish its efficacy and optimal use in this context.

More about bisabolol
More about Ulcerations (external)

Other ingredients used for Ulcerations (external)

Other health conditions supported by bisabolol

Products containing bisabolol