Evidence supporting the use of: Ficin
For the health condition: Ulcerations (external)

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Ficin, a proteolytic enzyme derived from the latex of the fig tree (Ficus carica), has a longstanding history of traditional use in wound care, particularly for the treatment of external ulcerations. Historical records and ethnobotanical sources indicate that ficin-containing fig latex has been applied topically to ulcers and wounds in various traditional medicine systems, including those of the Mediterranean and Middle Eastern regions. The rationale behind this usage is primarily based on ficin's enzymatic activity, which helps in debriding necrotic tissue and promoting wound cleaning, thereby potentially facilitating the healing process.

However, rigorous scientific studies evaluating ficin specifically for external ulcerations are limited. Most available data are either anecdotal or derived from in vitro or animal studies demonstrating ficin's proteolytic and debriding properties. Clinical evidence directly supporting its efficacy and safety in treating human ulcerations is sparse. Nevertheless, the traditional use persists, and ficin or fig latex preparations are sometimes employed in folk remedies for chronic wounds and ulcers. Given the lack of robust clinical trials, the evidence rating is moderate (2/5), reflecting that while there is a plausible mechanism and historical precedent, conclusive scientific validation is lacking.

More about ficin
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Products containing ficin

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